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Visar resultat 21 - 25 av 55 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Children Lost and Found : A bioarchaeological study of Middle Helladic children in Asine with a comparison to Lerna

    Författare :Anne Ingvarsson-Sundström; Robert Arnott; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Classical archaeology and ancient history; children; archaeology; osteology; Asine; Lerna; Middle Helladic; skeletons; age; subadults; graves; growth; health; weaning; mortality; fetuses; infants; mortuary ritual; Bronze Age.; Antikens kultur och samhällsliv; Classical archaeology and ancient history; Antikens kultur och samhälle; arkeologi; Archaeology;

    Sammanfattning : This study focusses on children’s living conditions during the Middle Helladic period in Greece. The primary material comprises disarticulated skeletal remains found in a stratigraphic context during the Swedish excavations of Asine in 1926: 4,583 fragments/complete bones. LÄS MER

  2. 22. From brain to muscle and back : novel approaches to harness the benefits of exercise

    Författare :Yildiz Kelahmetoglu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : As the world population is growing older and more sedentary every day, the need for new approaches to combat chronic diseases grows steadily. Physical exercise improves health and reduces the risk of developing a plethora of chronic diseases. LÄS MER

  3. 23. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia

    Författare :Marju Orho-Melander; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mutation; GYS2; GYS1; glycogen synthase; glycogen; insulin resistance; hypoglycaemia; liver glycogen synthase deficiency; glycogen storage disease type 0; Type 2 diabetes; metabolic syndrome; expression; chromosome 19; 19q13.3; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. LÄS MER

  4. 24. Enzymes involved in heparan sulfate chain elongation : Function of a novel family of tumor suppressors?

    Författare :Thomas Lind; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparan sulfate; biosynthesis; glycosyltransferase; EXT1; EXT2; UDP-glucosedehydrogenase; KfiC; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Sammanfattning : Heparan sulfate (HS) is a glycosaminoglycan associated with many physiological functions such as regulation of growth factor action and cell adhesion. The HS polysaccharide is synthesized by alternating addition of D-glucuronic acid (GlcA) and N-acetyl-D-glucosamine (GlcNAc) units from the corresponding UDP-sugar precursors. LÄS MER

  5. 25. Peptidergic innervation of periarticular tissue : a study in the rat

    Författare :Paul Ackermann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Immunohistochemistry; radioimmunoassay; pain measurement; Achilles tendon; collateral ligaments; joint capsules; tendon rupture; regeneration; peripheral nervous system; neuropeptides; delta opioid receptor;

    Sammanfattning : Painful musculo-skeletal disorders pose a tremendous burden on the healthcare system, the main reason being the limited knowledge of the underlying pathomechanisms and lack of specific treatment. Hypothetically, the peripheral nervous system in the musculo-skeletal tissues plays an important role in the regulation of pain, inflammation, vasoactivity and also tissue repair. LÄS MER