Sökning: "skeletal remains"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden skeletal remains.

  1. 1. Sensitive Identification Tools in Forensic DNA Analysis

    Författare :Hanna Edlund; Marie Allen; Niels Morling; Uppsala universitet; []
    Nyckelord :forensic genetics; STRs; Y-chromosome; Pyrosequencing; mitochondrial DNA; skeletal remains; DNA extraction; MEDICINE; MEDICIN; Medicinsk genetik; Medical Genetics;

    Sammanfattning : DNA as forensic evidence is valuable in criminal investigations. Implementation of new, sensitive and fast technologies is an important part of forensic genetic research. This thesis aims to evaluate new sensitive methods to apply in forensic DNA analysis including analysis of old skeletal remains. LÄS MER

  2. 2. Application of Mitochondrial DNA Analysis in Contemporary and Historical Samples

    Författare :Maria Lembring; Marie Allen; Niels Morling; Uppsala universitet; []
    Nyckelord :Forensic genetics; Mitochondrial DNA; HVI HVII; Population database; Haplotype; Haplogroup; Ancient DNA; Historical DNA samples; skeletal remains; Vasa museum; Medieval samples; Copernicus; Göring; Genetik; Genetics;

    Sammanfattning : The mitochondrion is a tiny organelle that is the power supplier of the cell and vital to the functioning of the body organs. Additionally it contains a small circular genome of about 16 kb, present in many copies which makes the mitochondrial DNA more viable than nuclear DNA. LÄS MER

  3. 3. Vascular effects of prostacyclin in cat skeletal muscle and in the traumatised rat brain

    Författare :Peter Bentzer; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reflection coefficient; cerebral blood flow; hydraulic conductivity; oedema; capilary filtration coefficient; endothelin-1; ATP-dependent potassium channels; Physiology; Fysiologi;

    Sammanfattning : Disturbances in microvascular function may be important for tissue damage in many disease states. Prostacyclin, a substance produced by endothelial cells, is important for the maintenance of normal vascular homeostasis and is a potential drug for treatment of microvascular dysfunction, but indications and optimal dosage remains to be established. LÄS MER

  4. 4. Identification of abnormally expressed genes in skeletal muscle contributing to insulin resistance and type 2 diabetes

    Författare :Xudong Huang; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; gene expression; high-fat intake; RT-PCR; mitochondrial genes; cathepsin L; Shc; IRS-2; IRS-1; GS; cDNA differential display; Insulin resistance; type 2 diabetes; sekretion; diabetologi;

    Sammanfattning : The metabolic defects of insulin resistance and type 2 diabetes can result from changes in gene expression and protein functions due to genetic and environmental influences. The aim of this study was to identify abnormally expressed genes associated with insulin resistance or type 2 diabetes, and further to test whether possible defects are inherited or acquired. LÄS MER

  5. 5. The role of exercise and exercise-related factors in the control of mitochondrial oxidative function

    Författare :Brandon Walsh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Skinned fibers; permeabilized fibers; skeletal muscle; exercise; mitochondria; ADP sensitivity; aerobic metabolism; training; eccentric; high intensity; creatine; phosphocreatine; inorganic phosphate; hydrogen ions;

    Sammanfattning : The effects of exercise and exercise-related factors on the control of mitochondrial oxidative function were investigated in human and rat skeletal muscle. Oxidative function was assessed through the measurement of oxygen consumption in chemically permeabilized (skinned) fibers. LÄS MER