Sökning: "skeletal muscle contraction"

Visar resultat 1 - 5 av 52 avhandlingar innehållade orden skeletal muscle contraction.

  1. 1. Structure and function of the cytoskeleton in cardiac and skeletal muscle

    Författare :Johanna Balogh; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP-receptor; Cardiovascular system; Kardiovaskulära systemet; cardiomyopathy; transgenic mice; skeletal muscle; heart; muscle contraction; cytoskeleton; desmin;

    Sammanfattning : We have examined the functional and structural roles of the cytoskeletal protein desmin in cardiac and skeletal muscles using a genetically modified mouse (Des-/-) with the desmin gene ablated. Desmin forms filaments at the Z-disks in the striated muscle sarcomere, have connections to the sarcolemma and most likely align sarcomeres and whole cells. LÄS MER

  2. 2. Myonuclear Organization and Regulation of Muscle Contraction in Single Muscle Fibres : Effects of Ageing, Gender, Species, Endocrine Factors and Muscle Size

    Författare :Rizwan Qaisar; Lars Larsson; Jo Bruusgaard; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single muscle cells; muscle nuclei; specific force; species; hypertrophy; mammals; ageing; gender; Physiology; Fysiologi;

    Sammanfattning : The skeletal muscle fibre is a syncitium where each myonucleus regulates the gene products in a finite volume of cytoplasm i.e., the myonuclear domain (MND). LÄS MER

  3. 3. Intensive Care Unit Muscle Wasting : Skeletal Muscle Phenotype and Underlying Molecular Mechanisms

    Författare :Sudhakar Reddy Aare; Larsson Lars; Rooyackers Olav; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute quadriplegic myopathy; gene expression; myosin; heat shock proteins; mechanical ventilation; myostatin; sepsis; corticosteroids; diaphragm; Clinical Neurophysiology; Klinisk neurofysiologi;

    Sammanfattning : Acute quadriplegic myopathy (AQM), or critical illness myopathy, is a common debilitating acquired disorder in critically ill intensive care unit (ICU) patients characterized by generalized muscle wasting and weakness of limb and trunk muscles. A preferential loss of the thick filament protein myosin is considered pathognomonic of this disorder, but the myosin loss is observed relatively late during the disease progression. LÄS MER

  4. 4. Human muscle spindles : complex morphology and structural organisation

    Författare :Jing-Xia Liu; William K. Ovalle; Umeå universitet; []
    Nyckelord :human; muscle spindle; intrafusal fiber; aging; biceps brachii; deep muscles of the neck; MyHC; mATPase; SERCA; anatomi; Human Anatomy;

    Sammanfattning : Muscle spindles are skeletal muscle mechanoreceptors that mediate the stretch reflex and provide axial and limb position information to the central nervous system. They have been proposed to play a major role in the pathophysiology of muscle pain. LÄS MER

  5. 5. Skeletal muscle fiber types in man : With special reference to anabolic signaling and mitochondrial bioenergetics

    Författare :Sebastian Edman; William Apro; Filip J Larsen; Abram Katz; Leigh Breen; Gymnastik- och idrottshögskolan; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mTORC1; THRIFTY; fiber type identification; muscle growth; aging; sarcopenia; mitochondrial function; oxphos; metabolism; Medicin Teknik; Medicine Technology;

    Sammanfattning : Human skeletal muscle consists of a mixture of slow-twitch (type I) and fast-twitch (type II) fibers. The type I fibers are endurance-oriented, with a metabolic system and infrastructure that supports aerobic metabolism. LÄS MER