Sökning: "size-based separation"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden size-based separation.

  1. 1. Microfluidic bases sample preparation for blood stream infections

    Författare :Sahar Ardabili; Aman Russom; Mats Nilsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sample-preparation; microfluidics; sepsis; size-based separation; selective cell-lysis; immune-based isolation; Biotechnology; Bioteknologi;

    Sammanfattning : Microfluidics promises to re-shape the current health-care system by transferring diagnostic tools from central laboratories to close vicinity of the patient (point-of-care). One of the most important operational steps in any diagnostic platform is sample preparation, which is the main subject in this thesis. LÄS MER

  3. 2. Novel microfluidic based sample preparation methods for rapid separation and detection of viable bacteria from blood for sepsis diagnostics

    Författare :Sharath Narayana Iyengar; Aman Russom; Jonas Tegenfeldt; KTH; []
    Nyckelord :microfluidics; Bioteknologi; Biotechnology;

    Sammanfattning : Sepsis is a serious medical condition characterized by a whole-body inflammatory response caused by bloodstream infection. The final stage of sepsis can lead to septic shock, multiple organ failure, and death. In early sepsis, the concentration of bacteria in the bloodstream is typically low, making diagnosis challenging. LÄS MER

  4. 3. Bioparticle Manipulation using Acoustophoresis and Inertial Microfluidics

    Författare :Muhammad Asim Faridi; Aman Russom; Martin Wiklund; Jonas Tegenfeldt; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biotechnology; Bioteknologi;

    Sammanfattning : Despite the many promising advances made in microfluidics, sample preparation remains the single largest challenge and bottleneck in the field of miniaturised diagnostics. This thesis is focused on the development of sample preparation methods using active and passive particle manipulation techniques for point of care diagnostic applications. LÄS MER

  5. 4. Acoustic manipulation for cell and spheroid cellomics

    Författare :Karl Olofsson; Martin Viklund; Maria Tenje; KTH; []
    Nyckelord :Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Sammanfattning : Ultrasonic standing wave (USW) particle manipulation has during the last two decades matured into a valuable tool to combine with microfluidics. Acoustophoresis, migration through sound, is the result of the acoustic radiation force acting on particles suspended in an acoustic field. LÄS MER

  7. 5. Microfluidic based isolation of circulating tumor cells from whole blood for cancer diagnostics

    Författare :Harisha Ramachandraiah; Aman Russom; Klas Hjort; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biotechnology; Bioteknologi;

    Sammanfattning : Detection of circulating tumor cells (CTC) in peripheral blood is indicative of early recognition of tumor progression and such an important biomarker for early diagnosis, staging, monitoring and prognosis of cancer. However, CTC are found in very low concentrations and reliable isolation of these rare cells is challenging. LÄS MER