Sökning: "size profiling"

Visar resultat 11 - 15 av 55 avhandlingar innehållade orden size profiling.

  1. 11. Expression profiling of human macrophages and atherosclerotic plaques to identify genes and mechanisms that modulate the development of atherosclerosis

    Författare :Daniel Hägg; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Macrophages play an important role in atherosclerosis, a disease that affects large and medium size arteries and causes clinical manifestations such as myocardial infarction or stroke. The aim of this thesis was to identify genes that are important in the development of atherosclerosis. LÄS MER

  3. 12. Exploring the diversity and evolution of giant viruses in deep sea sediments using genome-resolved metagenomics

    Författare :Disa Bäckström; Thijs J. G. Ettema; Anna J. Szekely; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metagenomics; binning; viruses; NCLDV; Megavirales; viral evolution.;

    Sammanfattning : Viruses are the most abundant biological entities on this planet, which is impressive considering that they are completely dependent on their hosts for reproduction. Recently the idea of what viruses are has changed dramatically, with the discovery of giant viruses that belong to the Nucleocytoplasmic Large DNA Viruses (NCLDV), such as Mimiviridae, Marseilleviridae, and the proposed families Pandoraviruses, and Pithoviruses. LÄS MER

  4. 13. Efficient methods for application performance analysis

    Författare :David Eklöv; Erik Hagersten; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Datavetenskap; Computer Science;

    Sammanfattning : To reduce latency and increase bandwidth to memory, modern microprocessors are designed with deep memory hierarchies including several levels of caches. For such microprocessors, the service time for fetching data from off-chip memory is about two orders of magnitude longer than fetching data from the level-one cache. LÄS MER

  5. 14. Gene expression patterns in human adipose tissue in relation to fat mass and adipose depot

    Författare :Kristina Linder Ekberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obesity, especially excess amount of abdominal fat, predisposes to a high risk for cardiovascular disease. Cancer cachexia is characterized by a specific loss of white adipose tissue (WAT) and skeletal muscle mass, and is associated with decreased survival and poor response to chemotherapy. LÄS MER

  7. 15. Refined diagnosis and prognosis in soft tissue sarcoma - genetic profiles, biomarkers and prognostic models

    Författare :Ana Carneiro; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MFH; microarrays; prognostic factors; metastasis; local recurrence; proliferation; Ki67; Top2a; p21; p27; S-phase fraction; erzin.;

    Sammanfattning : This work aimed at evaluate diagnosis and prognosis in soft tissue sarcoma (STS): In study I, 32K bacterial artificial chromosome (BAC) arrays and gene expression profiling were applied to 18 leiomyosarcomas and 31 undifferentiated pleomorphic sarcomas (UPS), with the aim of identifying molecular subtype signatures. Both the gains/losses profiles and the gene expression signatures revealed striking similarities between the two tumour types. LÄS MER