Sökning: "single-nucleotide polymorphisms"
Visar resultat 6 - 10 av 219 avhandlingar innehållade orden single-nucleotide polymorphisms.
6. Understanding the adaptive capacity of the bumblebee Bombus terrestris across native and novel environments
Sammanfattning : Anthropogenic stressors such as agricultural intensification, climate change, andincreased densities of non-native managed bees used for crop pollination arecontributing to bee declines. Understanding how and why bees have responded topast environmental changes is crucial for predicting future ones and enablingmitigation to maintain the functioning of both natural and agricultural ecosystems. LÄS MER
7. Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course
Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent destruction of synovial joints. Although its causes remain largely unknown, a substantial genetic contribution is known to exist. LÄS MER
8. The impact of gonadotropin receptor polymorphisms on human reproductive function
Sammanfattning : To date, approximately 15% of all couples worldwide suffer from infertility. The management include controlledovarian hyper-stimulation of the women with follicle-stimulating hormone (FSH) and semen analysis of the men,prior to in vitro fertilization (IVF) and transfer of the fertilized embryo to the uterine cavity. LÄS MER
9. Reproductive Factors and Breast Cancer - Parity, Breastfeeding and Genetic Predisposition in Relation to Risk and Prognosis
Sammanfattning : The aim of this thesis was to study reproductive factors and genetic polymorphisms in relation to breast cancer risk and survival. An important component of this was to investigate the risk of specific breast cancer subgroups. LÄS MER
10. Genetics of Parkinson's disease - with focus on genes of relevance for inflammation and dopamine neruon development
Sammanfattning : Abstract GENETICS OF PARKINSON’S DISEASE - WITH FOCUS ON GENES OF RELEVANCE FOR INFLAMMATION AND DOPAMINE NEURON DEVELOPMENT Introduction: The risk to be affected by Parkinson’s disease (PD) is considered to be influenced by genetic factors. In some rare cases of familial PD, mutations in some specific genes are known to cause the disease, but in the more common sporadic form of PD the causes are probably environmental factors interacting with genetic vulnerability. LÄS MER