Sökning: "single-cell"
Visar resultat 21 - 25 av 466 avhandlingar innehållade ordet single-cell.
21. Single cell analysis of checkpoints in G1
Sammanfattning : It is becoming evident that defective cell cycle regulation is an important property of the cancer cell. The restriction point (R), a G1 checkpoint after which cell cycle progression becomes independent of extracellular growth factors, is often aberrant in cancer cells. LÄS MER
22. Single-cell RNA sequencing as a tool to study panarthropod evolution
Sammanfattning : Panarthropoda is a monophyletic group comprised of arthropods and lobopods, molting animals with a segmented body, paired appendages, dorsal brain, and ventral nerve cords. Evolutionary Developmental Biology (EvoDevo) is an interdisciplinary field that seeks to understand how changes in development form the basis for variations in morphology and phenotypic evolution, including the genetic network underlying these processes. LÄS MER
23. Novel insights into protist diversity and niche adaptation using single cell transcriptomics
Sammanfattning : Protists are a polyphyletic group of microbes that represents the vast majority of eukaryotic diversity. Despite this, most sequencing efforts targeting eukaryotes have been focused on animals, fungi and plants. LÄS MER
24. Evolving the Methodology for Detection of Primary DNA Damage : Development, adaptation and assessment of the single cell gel electrophoresis (comet) assay
Sammanfattning : Deoxyribonucleic acid (DNA) is one of the most important molecules in nature. It is the fundamental carrier of evolutionary information and constitutes the genetic blueprint of all living organisms. Being the sole source of information, it is vital for the cell to transmit the correct genetic information from generation to generation. LÄS MER
25. From single-cell transcriptomics to single-molecule counting
Sammanfattning : RNA-sequencing (RNA-seq) technology has been progressing so fast in the last few years and made it possible to perform transcriptome analysis at single-cell level that was even unimaginable a few years before. Nowadays, the importance of gene expression analysis at the single-cell level is increasingly appreciated for the study of complex heterogeneous tissue. LÄS MER