Sökning: "single turnover"

Visar resultat 1 - 5 av 73 avhandlingar innehållade orden single turnover.

  1. 1. Into the Single-Verse : Subtle gene expression differences between virtually identical single cells are informative of gene regulation

    Författare :Marcel Tarbier; Marc Friedländer; Nils Blüthgen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Single-cell; quantitative; RNA biology; miRNA; functional genomics; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The ability to profile transcriptomes and proteomes in a high-throughput fashion in single cells has truly revolutionized functional genomics, and countless functional and regulatory insights have been based on these technologies. While major applications include the discovery of new cell types and the a posteriori sorting of cell populations, studies of gene expression noise and gene co-expression have made use of this inter-cellular heterogeneity in a genuine quantitative fashion. LÄS MER

  2. 2. Nanofluidic Scattering Microscopy for Single Particle Catalysis

    Författare :Björn Altenburger; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; label-free methods; Platinum; Nanofluidics; Single nanoparticle catalysis; Particle trapping; Hydrogen Peroxide decomposition; Colloidal particles; Dark field microscopy;

    Sammanfattning : Heterogeneous catalysis concerns material formulations – catalysts – that can assist a chemical reaction by improving its rate or selectivity, by lowering activation barriers and altering the energy landscape. The core of catalysts are often tiny metal particles that provide a large reaction surface at a small volume, as well as low coordination sites whose type and abundance depends on particle size and shape. LÄS MER

  3. 3. Leadership in human service organisations: Conceptions, strategies and preconditions to promote and maintain health at work

    Författare :Katrin Skagert; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; management; sickness absence; psychosocial factors; turnover; workplace health promotion; participation; trust; exit; sickness presenteeism;

    Sammanfattning : The aim of this thesis was to deepen knowledge of leaders’ conceptions, strategies and preconditions to promote and maintain health at work in human service organisations. Methods: The qualitative study I and prospective study II are both part of a research and development programme (The SAMS study) of workplace health promotion (WHP) projects and the setting was the City of Göteborg. LÄS MER

  4. 4. Nitric Oxide Reductase from Paracoccus denitrificans : A Proton Transfer Pathway from the “Wrong” Side

    Författare :Ulrika Flock; Pia Ädelroth; Simon de Vries; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; denitrification; nitric oxide reductase; heme copper oxidase superfamily; divergent member; proton transfer; electron transfer; single turnover; spectroscopy; periplasm; glutamate; proton pathway; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Denitrification is an anaerobic process performed by several soil bacteria as an alternative to aerobic respiration. A key-step in denitrification (the N-N-bond is made) is catalyzed by nitric oxide reductase (NOR); 2NO + 2e- + 2H+ → N2O + H2O. LÄS MER

  5. 5. Nanofluidics as a tool for parallelized single nanoparticle characterization: Fluorescence single nanoparticle catalysis and size determination through 1D Brownian motion

    Författare :Sune Levin; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; dark field microscopy; single nanoparticle catalysis; heterogenous catalysis; particle tracking; Brownian motion; fluorescence microscopy; nanofluidics;

    Sammanfattning : Nanoparticles exist widely in nature and are objects of study in many scientific disciplines due to their high performance in a wide range of applications. With modern techniques that facilitate creating and shaping of nanoparticles into ever more complex shapes and compositions, characterization of particle properties is essential. LÄS MER