Sökning: "single nucleotide polymorphism SNP"

Visar resultat 21 - 25 av 118 avhandlingar innehållade orden single nucleotide polymorphism SNP.

  1. 21. Genetic variation at the human tissue-type plasminogen activator locus

    Författare :Per Ladenvall; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tissue-type plasminogen activator; single-nucleotide polymorphism; vascular release; myocardial infarction; enhancer; Sp1.;

    Sammanfattning : Tissue-type plasminogen activator (tPA) is the key initiator of intravascular fibrinolysis. Family studies suggest that tPA release is regulated by hereditary factors. LÄS MER

  3. 22. Characterisation of weak and null phenotypes in the KEL and JK blood group systems

    Författare :Elisabet Sjöberg Wester; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; null; SNP; Kidd; JK; Blood group; Kell; KEL; weak;

    Sammanfattning : The focus of this thesis is on KEL and JK, two clinically important blood group systems, and the investigations of blood samples with aberrant antigen expression as in null and weak phenotypes, or with a phenotype that does not correspond to genotype. With the increasing use of DNA assays based on single nucleotide polymorphisms for blood group prediction, it is important to characterize the blood-groupencoding genes. LÄS MER

  4. 23. Multiplex markers in a plant breeding perspective

    Författare :Mats Hansen; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant biochemistry; plant breeding; SNP; RAPD; molecular markers; AFLP; Växtbiokemi;

    Sammanfattning : Plant breeding is largely depending on the repeated selection for desirable traits. This process is both time and labour consuming, making the development of commercial plant varieties a slow and costly activity. LÄS MER

  5. 24. Eosinophil Cationic Protein : Expression Levels and Polymorphisms

    Författare :Jonas Byström; Helene Rosenberg; Uppsala universitet; []
    Nyckelord :Medical sciences; Eosinophils; Neutrophils; Monocytes; Macrophages; mRNA; eosinophil cationic protein; DNA; polymorphism; Hodgkin Lymphoma; asthma; allergy; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : The eosinophil cationic protein (ECP) is usually associated with the eosinophil granulocyte. In this thesis the presence and production of this protein has been studied in two other cells. The circulating monocyte was found to contain ECP mRNA and small amounts of ECP, one thousand times less than that found in the eosinophil. LÄS MER

  7. 25. On the influence of dopamine-related genetic variation on dopamine-related disorders

    Författare :Olle Bergman; Göteborgs universitet; []
    Nyckelord :dopamine; neurodevelopment; amygdala; schizophrenia; Parkinson s disease; social anxiety disorder; ADHD; PITX3; LMX1A; LMX1B; BDNF; DAT; SNP; genes; genetics; BDNF;

    Sammanfattning : Rationale: Dopamine synthesizing neurons are involved in a wide variety of functions. The most prominent dopamine pathways originate in the midbrain. The development, function and survival of these dopaminergic neurons are under the influence of numerous transcription and neurotrophic factors. LÄS MER