Sökning: "simvastatin"
Visar resultat 21 - 25 av 26 avhandlingar innehållade ordet simvastatin.
21. Leukocytes and Coronary Artery Disease : Experimental and Clinical Studies
Sammanfattning : Tissue factor (TF) is the initiator of the coagulation cascade. Monocytes do not normally express TF, but can be induced to do so by certain stimuli. Aberrant TF expression is important in the thrombotic complications of bacterial sepsis, certain malignancies and coronary artery disease (CAD). LÄS MER
22. Therapeutic myocardial angiogenesis and its pharmacological modulation
Sammanfattning : Angiogenesis is the formation of new blood vessels induced by the proliferation and migration of endothelial cells. Because angiogenesis is a complex process, therapeutic efficacy may be improved by overexpression of combined angiogenic factors. LÄS MER
23. Platelet function in hyperlipoproteinemia and effects of lipid-lowering treatment
Sammanfattning : Coronary atherosclerosis and thrombus formation on fissuring atherosclerotic plaques are key events in the development of coronary artery disease. Hyperlipoproteinemia induces atherosclerosis but may also exert direct prothrombotic effects via platelet activation. LÄS MER
24. CYP26B1 as regulator of retinoic acid in vascular cells and atherosclerotic lesions
Sammanfattning : Cardiovascular disease (CVD), currently the most common cause of morbidity and mortality worldwide, is caused mainly by atherosclerosis. Atherosclerosis is a chronic multifocal, immunoinflammatory, fibroproliferative disease of medium and large arteries. LÄS MER
25. Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis
Sammanfattning : The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate to several cardiovascular risk factors, e.g. hypertension and hyperlipidemia. LÄS MER