Sökning: "simvastatin"

Visar resultat 11 - 15 av 26 avhandlingar innehållade ordet simvastatin.

  1. 11. Signaling mechanisms in Streptococcal M1 proteininduced inflammation and injury in the lung

    Författare :Songen Zhang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. Acute lung injury is recognized as a key component in the pathophysiology of streptococcal M1 proteininduced inflammation. LÄS MER

  3. 12. Effects of lipid-lowering treatment on platelet function and hemostatic mechanisms in diabetic patients : influence of chronic kidney disease and inflammatory parameters

    Författare :Tora Almquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetes mellitus (DM) and chronic kidney disease (CKD) are both associated with increased cardiovascular morbidity and mortality, and the risk is even higher when they are concurrent. Both diseases are considered to be prothrombotic states with increased inflammatory activity and major disturbances in the hemostasis. LÄS MER

  4. 13. Pleiotropic effects of HMG-CoA reductase inhibitors : studies in vitro and in vivo

    Författare :Cristine Skogastierna; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease (CVD) is the prime cause of death in industrialized countries, resulting from the progression of atherosclerotic lesions. An increased level of plasma cholesterol, particularly within low-density lipoproteins, is a principle risk factor, but also elevated triglycerides and low levels of high-density lipoprotein cholesterol. LÄS MER

  5. 14. Establishment of new potential biomarkers for cardiometabolic diseases

    Författare :Karin Littmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiometabolic diseases is a growing health issue worldwide. New knowledge about the pathophysiological processes have been gained and several research discoveries have contributed to better management of the diseases. Even so, the prognosis, diagnosis, and treatment of cardiometabolic diseases needs to be further improved. LÄS MER

  7. 15. Drug-drug interactions : from knowledge base to clinical impact

    Författare :Marine Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Drug usage has increased steadily, and the more drugs used, the higher the risk for adverse effects or loss of effect due to drug-drug interactions. For drug prescribers it is difficult to know what drugs a patient is taking and whether they interact. LÄS MER