Sökning: "silent"

Visar resultat 41 - 45 av 221 avhandlingar innehållade ordet silent.

  1. 41. Streptococcal and staphylococcal tissue infections : therapeutic challenges and opportunities

    Författare :Helena Bergsten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pyogenes and Staphylococcus aureus have been leading causes of human infections throughout history. S. pyogenes is of the top-ten pathogens responsible for most death globally, 0.5 million deaths per year. LÄS MER

  3. 42. The Significance of IgG Antibodies against Tissue Transglutaminase in Coeliac Disease

    Författare :Ingrid Dahlbom; Birgitta Heyman; Tony Hansson; Knut Lundin; Uppsala universitet; []
    Nyckelord :Immunology; Coeliac disease; Tissue transglutaminase; Endomysium; IgG antibodies; Immunologi;

    Sammanfattning : Coeliac disease (CD) is a multifactorial disease of the small intestine. In genetically predisposed individuals the, ingestion of cereals leads to a remodulation of the mucosal architecture, and the production of autoantibodies against tissue transglutaminase (tTG). The treatment is a lifelong gluten-free diet. LÄS MER

  4. 43. From stem cell to neuron : a Sox perspective

    Författare :Maria Bergsland; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The differentiation of stem cells into the more than 100 billion neurons that compose the central nervous system (CNS) is one of the most remarkable transformations during vertebrate development. A central problem of this process is how neural lineage selection initially is specified in pluripotent stem cells and maintained during the course of neurogenesis. LÄS MER

  5. 44. Regulators of chromatin and transcription in Drosophila

    Författare :Filip Crona; Mattias Mannervik; Fernando Azorin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transcription; chromatin; co-regulators; CBP; lysine demethylase; KDM4A; Brakeless; Drosophila; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : Development of multicellular organisms is achieved by organized temporal and spatial patterns of gene expression leading to cell differentiation. Chromatin regulators control how the DNA is utilized by altering access of proteins to DNA and thereby function as co-factors in transcription. LÄS MER

  7. 45. Hereditary Breast Cancer in South Sweden. Early findings from studies on the role of BRCA1

    Författare :Oskar Thor Johannsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; survival analysis; CGH; mRNA in situ hybridization; germline mutations; LOH; Breast neoplasm; BRCA1; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : The thesis presents the results from investigations into the role of BRCA1 in hereditary cancer in South Sweden. Loss of heterozygosity (LOH) studies found loss of the wildtype allele of BRCA1 to be common in BRCA1 associated breast cancer, but due to the high degree of LOH on chr. LÄS MER