Sökning: "sib prevalence"
Hittade 5 avhandlingar innehållade orden sib prevalence.
1. On Power Estimation and Score Predictions in Affected Sib-Pair Linkage Analysis
Sammanfattning : This thesis consists of three papers in statistical genetics, with the emphasis on affected sib-pair linkage analysis. In Paper A, a method to derive the power of linkage analysis in genome scans, using a stepwise approach, is presented. LÄS MER
2. Genetic Studies of Alzheimer's Disease
Sammanfattning : Patients with Alzheimer's disease (AD) often have a family history of the disease, implicating genetics as a major risk factor. Three genes are currently known to cause familial early-onset AD (65 years), only the APOE gene has repeatedly been associated to AD, where the ε4 allele increases disease risk and decreases age at onset. LÄS MER
3. Gene mapping of atopic dermatitis
Sammanfattning : Atopic dermatitis is a hereditary, pruritic, inflammatory and chronic skin disease that typically presents in early childhood. It is often associated with other atopic manifestations, such as asthma, allergic rhinoconjunctivitis, and elevated total and/or allergen-specific serum lgE levels. LÄS MER
4. Aspects of Helicobacter pylori transmission
Sammanfattning : The bacterium Helicobacter pylori infects the gastric mucosa of about half of the world's population. The infection causes gastritis and contributes to the development of peptic ulcer disease and gastric cancer. H. LÄS MER
5. Genetic mapping and association analysis in multiple sclerosis
Sammanfattning : Multiple sclerosis (MS) is a chronic neurological disease. Epidemiological studies have shown evidence for both environmental and genetic involvement of the disease. LÄS MER