Sökning: "sialylmimetics"

Hittade 1 avhandling innehållade ordet sialylmimetics.

  1. 1. Design and Synthesis of Sialic Acid Conjugates as Inhibitors of EKC-causing Adenoviruses

    Författare :Susanne Johansson; Jan Kihlberg; Mikael Elofsson; Stefan Oscarson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sialic acid; sialylmimetics; sialylation; multivalency; glycoconjugates; adenovirus; antiviral agents; epidemic keratoconjunctivitis; Bioorganic chemistry; Bioorganisk kemi;

    Sammanfattning : The combat against viral diseases has been, and still is, a major challenge in the field of drug development. Viruses are intracellular parasites that use the host cell ma-chinery for their replication and release. Therefore it is difficult to target and destroy the viral particle without disturbing the essential functions of the host cell. LÄS MER