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Visar resultat 1 - 5 av 49 avhandlingar som matchar ovanstående sökkriterier.
1. Optimizing fluid therapy in the hemodynamically unstable patient
Sammanfattning : .... LÄS MER
2. Hypothermia as an adjunctive therapy in Acute Myocardial Infarction and Cardiogenic Shock
Sammanfattning : INTRODUCTION: Reperfusion therapy in patients with an ongoing ST-elevation myocardial infarction (STEMI) is to re-establish coronary flow in the epicardial arteries as soon as possible in order to reduce infarct size and associated complications. Hypothermia has in experimental studies been shown to reduce infarct size. LÄS MER
3. Disease-causing Keratin Mutations and Cytoskeletal Dysfunction in Human Skin : In vitro Models and new Pharmacologic Strategies for Treating Epidermolytic Genodermatoses
Sammanfattning : Epidermolysis bullosa simplex (EBS) and epidermolytic ichthyosis (EI) are rare skin fragility diseases characterized by intra-epidermal blistering due to autosomal dominant-negative mutations in basal (KRT5 or KRT14) and suprabasal (KRT1 or KRT10) keratin genes, respectively. Despite vast knowledge in the disease pathogenesis, the pathomechanisms are not fully understood, and no effective remedies exist. LÄS MER
4. Aspects of hepatoduodenal trauma and fluid therapy in hemorrhagic shock
Sammanfattning : Traumatic injury is the leading cause of death among young adults and children, accounting for 5 million deaths worldwide on an annual basis. In Sweden alone, 2500 individuals succumb to traumatic injuries yearly. Beyond the burden of death, injuries contribute to a large proportion of disability. LÄS MER
5. Strain echocardiography in the critically ill patient : Studies in patients with septic shock and subarachnoid haemorrhage
Sammanfattning : In this thesis, strain echocardiography by two-dimensional speckle tracking imaging (2D-STI), was used for the evaluation of left ventricular (LV) and right ventricular (RV) function in critically ill patients with septic shock and subarachnoid haemorrhage. The aims were to: 1) investigate the value of strain echocardiography for the early detection of LV and RV dysfunction not diagnosed with conventional echocardiography in severe sepsis and septic shock, 2) to study the effects of norepinephrine on RV systolic function and pulmonary haemodynamics in patients with norepinephrine-dependent septic shock 3) evaluate the use of strain echocardiography for detection of myocardial injury in patients with subarachnoid haemorrhage (SAH) and 4) study the impact of general anaesthesia and positive pressure ventilation (PPV) on RV and LV myocardial longitudinal strain. LÄS MER