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Visar resultat 1 - 5 av 470 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Binding of radiographic contrast media to serum proteins : a clinical and experimental investigation of their adverse effects through influence on active steroid hormone levels

   Författare :Staffan Wirell; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adverse reactions; ioglycamide; metrizamide; protein binding radiographic contrast media; separation techniques; serum proteins; steroid sex hormone levels;

   Sammanfattning : .... LÄS MER

3. 2. Galectin binding proteins in serum and bronchoalveolar lavage -in healthy and pathological conditions

   Författare :Cecilia Cederfur; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; glycoprotein; asthma; bronchoalveolar lavage; galectin binding protein; galectin ligand; galectin; serum;

   Sammanfattning : Galectins are carbohydrate binding proteins, implicated in conditions of both inflammation and cancer. Connections between chronic inflammation and cancer are proposed by the increased remodelling and proliferation that occurs, leading to enhanced survival and proliferation of malignant cells. LÄS MER

4. 3. Array-based identification of disease-associated proteins

   Författare :Maria Mikus; Peter Nilsson; Jochen M. Schwenk; Ina Schuppe-Koistinen; Dolores Cahill; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity proteomics; Antibody array; Antigen array; Amyotrophic lateral sclerosis; Asthma; Atopic dermatitis; Biomarker discovery; Drug-induced liver injury; Microarray; Plasma; Protein microarray; Protein profiling; Serum; Suspension bead array; Bioteknologi; Biotechnology;

   Sammanfattning : To increase our understanding of the human body in both health and disease, proteins can be studied in samples such as plasma and serum to provide a molecular profile of the physiological status. In the work presented in this thesis, array-based methods were used to study associations of protein and autoantibody profiles with disease. LÄS MER

5. 4. Serum proteins in type 1 diabetes

   Författare :Nancy Dekki Wenna; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : We have previously shown that there are patients with type 1 diabetes T1D whose sera interfere with cytoplasmic free Ca2+-concentration ([Ca2+]i), resulting in �-cell apoptosis. In this study the frequency of sera, that induces this effect, was found to be around 35% in T1D patients, and 25% in first degree relatives (FDR) of T1D patients. LÄS MER

7. 5. Affinity assays for profiling disease-associated proteins in human plasma

   Författare :Sanna Byström; Jochen M. Schwenk; Claudia Fredolini; Peter Nilsson; Jennifer Van Eyk; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; affinity proteomics; immunoassay; antibody microarray; suspension bead array; protein profiling; immuno-capture; plasma; serum; cerebrospinal fluid; biomarker discovery; multiple sclerosis; malignant melanoma; mammographic breast density; Bioteknologi; Biotechnology;

   Sammanfattning : Affinity-based proteomics offers opportunities for the discovery and validation of disease-associated proteins in human body fluids. This thesis describes the use of antibody-based immunoassays for multiplexed analysis of proteins in human plasma, serum and cerebrospinal fluid (CSF). LÄS MER