Sökning: "serum bone markers"

Visar resultat 16 - 20 av 48 avhandlingar innehållade orden serum bone markers.

  1. 16. Role of tartrate-resistant acid phosphatase in bone remodeling

    Författare :Laia Mira-Pascual; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tartrate-resistant acid phosphatase is a metalloenzyme that exists as two isoforms: the monomeric TRAP 5a and the proteolytically cleaved TRAP 5b, responsible for phosphatase activity, which is highly expressed in osteoclasts (OCs). TRAP 5b has been used as a serum marker of bone resorption, as it correlates with the absolute number of OCs and with resorption markers such as CTX-I. LÄS MER

  3. 17. Obstructive pulmonary disease : Studies of acute exacerbations and immunologic status

    Författare :Inger Dahlén; Uppsala universitet; []
    Nyckelord :Medical sciences; asthma; COPD; acute exacerbations; inflammatory markers; psychologicalfactors; bone markers; immunological skin tests; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : In this thesis, different aspects of the treatment and care of patients with asthma and chronic obstructive pulmonary disease (COPD) have been studied.In a study of 50 patients seeking medical care for an acute exacerbation of asthma or COPD, we studied inflammatory markers in blood, sputum and urine. LÄS MER

  4. 18. Early parathyroidectomy in mild primary hyperparathyroidism: Effects on heart and bones

    Författare :Erik Almqvist; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; parathyroidectomy; hyperparathyroidism; bone metabolism; testosterone; myocardial hypertrophy; cardiac function; echocardiography; radionuclide angiography; natriuretic peptide; Surgery; orthopaedics; traumatologi; ortopedi; traumatology; Kirurgi;

    Sammanfattning : There is an ongoing controversy regarding how to take care of patients with mild primary hyperparathyroidism (PHPT). Some recommend surgical treatment at diagnosis, others just follow-up as long as there is no evidence of disease progression. LÄS MER

  5. 19. Regulation of cytokine receptors and activity markers in eosinophilic inflammatory processes

    Författare :Cecilia Hellman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The eosinophil is an important effector cell in allergic inflammation and asthma and an increased number of eosinophils and eosinophil-derived cytotoxic proteins have been found in blood and airways of allergic patients. The life cycle of the eosinophil starts with differentiation of bone marrow progenitor cells. LÄS MER

  7. 20. Studies on bone and mineral disorders in CKD : determinants and survival implications

    Författare :Ting Jia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Disruptions in mineral metabolism occur already at an early stage of chronic kidney disease (CKD) and may eventually lead to a complex of CKD - mineral and bone disorders (CKD-MBD) characterized by alterations of the mass, turnover rate, mineralization and strength of bones, and high risk of vascular calcification, fractures and other complications resulting in worse survival. The aim of this thesis was to increase the understanding of some aspects of CKD-MBD with special emphasis on clinical and laboratory determinants and implications for clinical outcome. LÄS MER