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Visar resultat 1 - 5 av 48 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Developing knee joint osteoarthritis: Clinical, radiographical and biochemical features

   Författare :Ingemar Petersson; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone markers; cartilage markers; WOMAC; SF-36; function; health status quality-of-life; radiography; epidemiology; knee pain; Knee joint; osteoarthritis; bone scan; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

   Sammanfattning : The aim of this project was to study clinical, radiographical and biochemical features of developing, symptomatic knee osteoarthritis (OA) prospectively in individuals aged 35-54 from the general population. A questionnaire to a random sample of 2 000 individuals in the district of Laholm, Sweden, identified 279 individuals (15% of the population) with chronic (>3 months) knee pain. LÄS MER

3. 2. Molecular and clinical studies of cartilage and bone macromolecules in arthritis

   Författare :Bengt Månsson; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Prognosis; Tissue damage; Bone markers; Cartilage markers; Rheumatoid arthritis; Psoriatic arthritis; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

   Sammanfattning : The pathogenesis of inflammatory arthritides include synovial inflammation and joint tissue destruction. Tissue destruction has traditionally been regarded a consequence of inflammation, but recent observations indicate that the processes are not always closely linked and may proceed uncoupled. LÄS MER

4. 3. Bone alkaline phosphatase isoforms in chronic kidney disease : mineral and bone disorder

   Författare :Mathias Haarhaus; Per Magnusson; Anders Fernström; Bengt Lindholm; Goce Spasovski; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Chronic kidney disease (CKD) is associated with increased mortality and cardiovascular complications. Disturbances in mineral metabolism occur early In study I we identified the novel BALP isoform Blx in 20% of patients with mild to moderate CKD. LÄS MER

5. 4. Vitamin D, bone turnover markers and hCAP-18 in children with hemato-oncological diseases

   Författare :Natalja Jackmann; Per Frisk; Outi Mäkitie; Jan Gustafsson; Anna Sällfors Holmqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vitamin D; pediatric cancer; leukemia; bone marrow failure; hCAP-18; bone turnover markers; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Children with hemato-oncological diseases may have significant skeletal morbidities. Vitamin D is essential for the maintenance of skeletal health and may also be important for immunological functions and cancer outcomes. LÄS MER

7. 5. Novel Insights into Inflammatory Disturbed Bone Remodelling

   Författare :Elin Kindstedt; Pernilla Lundberg; Östen Ljunggren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone; osteoblast; osteoclast; chemokines; CCL11; periodontitis; rheumatoid arthritis; innate lympoid cells; odontologi; Odontology; immunologi; Immunology; biology; biologi; reumatologi; rheumatology;

   Sammanfattning : Bone is a dynamic tissue that is continuously remodelled, a process that requires equal amounts of osteoclastic bone resorption and osteoblastic bone formation. Inflammation may disturb the equilibrium and result in local and/or systemic bone loss. Negative bone mass balance occurs in several chronic inflammatory diseases, e.g. LÄS MER