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Visar resultat 1 - 5 av 549 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Capacitive Biosensor - A Tool for Ultrasensitive Analysis : Application in Clinical Analysis and Process Monitoring

   Författare :Kosin Teeparuksapun; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capacitive Biosensor; Ultrasensitive Analysis; Clinical Analysis; Bioprocess Monitoring; Human Serum Albumin; HIV-1 p24; Host Cell Proteins; Protein A; Current Pulse;

   Sammanfattning : Increasing demands for highly sensitive, accurate, fast and portable analytical assays have led to the development of new analytical tools. The integration of highly specific biological sensing elements and appropriate transducers has enabled design of even more efficient biosensor devices for the detection of target substances. LÄS MER

3. 2. Effects of Dehydration and Blockade of the Renin-Angiotensin System in the One-humped Camel (Camelus dromedarius)

   Författare :Mahmoud Al Haj; Fred Nyberg; Santi Spampinato; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood; biochemical analysis; catecholamine; colorimetric assay; cortisol; dehydration; dromedary camel; glutathione; hematological analysis; HPLC; insulin- like growth factor-1; losartan; plasma; receptors; radioimmunoassay; serum; Pharmaceutical Science; Farmaceutisk vetenskap;

   Sammanfattning : The one-humped or the dromedarian camel is a pseudo-ruminant mammal, well adapted to the hot and dry climates of the desert. Its ability to withstand torrid heat and extreme desiccation is of paramount importance to its survival. LÄS MER

4. 3. Impaired reparative processes in particular related to hyaluronan in various cutaneous disorders : a structural analysis

   Författare :Ulf Bertheim; Bengt Gerdin; Umeå universitet; []
   Nyckelord :hyaluronan; scar tissue; diabetes mellitus; basal cell carcinoma; skin; wound healing; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

   Sammanfattning : Cutaneous reparative processes, including wound healing, are highly developed procedures in which a chain of actions occurs to reconstitute the function of the wounded tissue. To prevent a delayed or excessive reparative process it is important to understand how this procedure develops and is maintained. LÄS MER

5. 4. Antibody-based bead arrays for high-throughput protein profiling in human plasma and serum

   Författare :Kimi Drobin; Jochen M. Schwenk; Peter Nilsson; Ulrika Qundos; Angela Silveira; Maria Pernemalm; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; affinity proteomics; immunoassay; antibody microarray; suspension bead array; protein profiling; plasma; serum; biomarker discovery; osteoporosis; inflammatory bowel disease; Crohn s disease; ulcerative colitis; Medical Technology; Medicinsk teknologi;

   Sammanfattning : Affinity-based proteomics utilizes affinity binders to detect target proteins in a large-scale manner. This thesis describes a high-throughput method, which enables the search for biomarker candidates in human plasma and serum. LÄS MER

7. 5. Compact-disc microfluidic methods for characterization of therapeutic antibodies : Analysis of post-translational modifications

   Författare :Thi Thuy Tran; Gunnar Thorsén; McLean John; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microfluidic CD; therapeutic antibodies; post-translational modifications; glycosylation profiling; multivariate statistical analysis; MALDI-MS; Analytical Chemistry; analytisk kemi;

   Sammanfattning : Characterization of post-translational modifications (PTMs) of therapeutic proteins is very important during the bioprocess development to maintain desired product quality and during the submission process to regulatory authorities for product approval. Monitoring glycosylation in pharmacokinetic studies can be useful to evaluate the dependence of clearance rates on different glycoforms. LÄS MER