Sökning: "serotype switching"
Hittade 4 avhandlingar innehållade orden serotype switching.
1. Development of novel vaccine strains of Vibrio cholerae and studies on the role of serotype in epidemic spread of cholera
Sammanfattning : Cholera, caused by bacterium Vibrio cholerae O1, is a severe diarrheal disease with an estimated 3-5 million cases and more than 140 000 deaths every year particularly affecting children under 5 years of age. It can be found all over the world and often causes cholera in places where access to clean water or proper sanitary facilities are limited or compromised. LÄS MER
2. Molecular epidemiology of streptococcus agalactiae : mobile elements as genetic markers
Sammanfattning : Streptococcus agalactiae, also designated group B streptococcus (GBS), is a Gram-positive coccus, and it is an important pathogen that causes invasive disease in neonates, pregnant adults, and non-pregnant adults with predisposing conditions. The group II intron GBSi1 is one of the major mobile genetic elements identified in S. agalactiae. LÄS MER
3. Mechanisms for pneumococcal meningitis and a new vaccine platform to raise a serotype-independent protection in the host
Sammanfattning : Streptococcus pneumoniae is a highly relevant pathogenic bacterium, responsible for a large fraction of deaths and disease morbidity in the world. The pneumococcus remains the leading cause of life-threatening pneumonia, septicemia and meningitis beyond neonatal age, despite global implementation of vaccination programs. LÄS MER
4. Development of Adenoviral Vectors for Studying Hematopoietic Stem Cell Function
Sammanfattning : Hematopoietic stem cells (HSCs) are defined by their capacity to self-renew and differentiate into all hematopoietic cell lineages. Postnatally, HSCs reside predominantly in the bone marrow and are relatively rare, but important cells because of their therapeutic potential in bone marrow transplantation protocols and in their involvement in the origin of certain leukemias. LÄS MER