Sökning: "serial femtosecond x-ray crystallography"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden serial femtosecond x-ray crystallography.

1. 1. Structural studies of ba3-type cytochrome c oxidase using serial crystallography and X-ray absorption spectroscopy

   Författare :Doris Zoric; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ba3-type cytochrome c oxidase; structural biology; X-rays; serial X-ray crystallography; X-ray absorption spectroscopy; enzyme reaction dynamics;

   Sammanfattning : Cytochrome c oxidase (CcO) catalyses the reduction of molecular oxygen to water while the energy released in this process is used transport protons “up-hill” across an energy transducing biological membrane, creating a proton-motive force for ATP synthesis. Given its key role in energy transduction in organisms, proton pumping has been extensively studied across species. LÄS MER

3. 2. Simulations of ultrafast photon-matter interactions for molecular imaging with X-ray lasers

   Författare :Ibrahim Eliah Dawod; Nicusor Timneanu; Carl Caleman; Adrian P. Mancuso; Lars Schäfer; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; X-ray free-electron laser; molecular dynamics; radiation damage; plasma simulations; density functional theory¸ coherent diffractive imaging; protein structure; X-ray crystallography; single particle imaging;

   Sammanfattning : Biological structure determination has had new avenues of investigation opened due to the introduction of X-ray free-electron lasers (XFELs). These X-ray lasers provide an extreme amount of photons on ultrafast timescales used to probe matter, and in particular biomolecules. LÄS MER

4. 3. Advances in Biomolecular Imaging with X-ray Free-Electron Lasers

   Författare :Christofer Östlin; Carl Caleman; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; XFEL; serial femtosecond x-ray crystallography; single particle imaging; radiation damage; GROMACS; Cretin; computer simulation;

   Sammanfattning : Utilizing X-rays to solve molecular structures has proven to be an immensely powerful and im- portant scientific technique. The invention of X-ray crystallography has allowed for countless breakthroughs in chemistry, biology and material science and remains the number one method used for structural determination today. LÄS MER

5. 4. X-ray free-electron laser based methods for structural and ultrafast dynamics studies of a photosynthetic reaction centre

   Författare :David Arnlund; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; WAXS; wide-angle x-ray scattering; XFEL; x-ray free-electron laser; reaction center; structural biology; ultrafast dynamics;

   Sammanfattning : Life on earth is fuelled by the energy of sunlight, which must first be captured and converted into a chemical energy form useful to the cell. This process is known as photosynthesis and the major pathway of this energy conversion is via photosynthetic reaction centres. LÄS MER

7. 5. Advances in Membrane Protein Structural Biology: Lipidic Sponge Phase Crystallization, Time-Resolved Laue Diffraction and Serial Femtosecond Crystallography

   Författare :Linda C Johansson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Serial femtosecond crystallography; Lipidic sponge phase crystallization; Membrane protein crystallization; X-ray free-electron laser;

   Sammanfattning : Membrane proteins carry out many essential tasks in cells such as signaling and transport, or function as electron carriers in photosynthesis and cellular respiration. The aim of this thesis has been to develop new and improve existing techniques for elucidating the structure and function of membrane proteins. LÄS MER