Sökning: "sequence identification"

Visar resultat 16 - 20 av 277 avhandlingar innehållade orden sequence identification.

  1. 16. Identification and characterization of DNA sequence variants associated with multiple myeloma

    Författare :Mina Ali; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :Multiple myeloma; inherited susceptibility; genome-wide association study; ELL2; expression quantitative trait loci;

    Sammanfattning : Multiple myeloma (MM) is the second most common hematologic malignancy. The disease is characterized by an uncontrolled growth of malignant plasma cells in the bone marrow, producing a monoclonal immunoglobulin (“M protein”) that can be detected in peripheral blood. LÄS MER

  2. 17. Genomic feature identification in trypanosomatid parasites

    Författare :Daniel Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Trypanosoma cruzi; genome sequence; bioinformatics; gene finding; Trypanosoma brucei; Leishmania major; strand asymmetry; trans splicing; polyadenylation; post-transcriptional control; uAUGs.;

    Sammanfattning : The trypanosomatid parasites cause death and suffering, among humans as well as livestock. Current drugs lack efficacy and cause severe side effects, and no vaccines are available. Increased knowledge of the biology of the parasites is vital for the development of new drugs. LÄS MER

  3. 18. Image sequence analysis of complex objects : law enforcement and defence applications

    Författare :Lena Klasén; Pierre Margot; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The objective of this research is image sequence analysis of complex objects. The term complex is here used for describing that the object simultaneously articulates and deforms. LÄS MER

  4. 19. Computational identification of non-coding RNAs

    Författare :Paul Piccinelli; Göteborgs universitet; []
    Nyckelord :RNase P; RNase MRP; IRE; non-coding RNA; secondary structure;

    Sammanfattning : A large amount of genomic information is now becoming available. Suitable bioinformatic tools to organize and analyze this vast amount of information are therefore important. In the case of protein genes, the majority of these may be correctly identified using standard search methods that are based on sequence alignment. LÄS MER

  5. 20. Identification of autoantigens in multiple sclerosis

    Författare :Mattias Bronge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system in which cells from primarily the adaptive immune system infiltrate the brain and spinal cord, leading to inflammation and demyelination. Debuting primarily between 20-40 years of age and with a prevalence in Sweden of ~0. LÄS MER