Sökning: "sequence identification"

Visar resultat 11 - 15 av 277 avhandlingar innehållade orden sequence identification.

1. 11. Computational Prediction Models for Proteolytic Cleavage and Epitope Identification

   Författare :Liwen You; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; medical informatics; biomathematics biometrics; Bioinformatics; SVM; sequence analysis; rule extraction; protease-peptide interaction; OSRE; MHC; immunology; HIV; hierarchical method; HCV; Gaussian process; false positive; epitope; cleavage specificity; cleavage prediction; binding affinity; caspase; Bioinformatik; medicinsk informatik; biomatematik; Computer science; numerical analysis; systems; control; Datalogi; numerisk analys; system; kontroll; Binding affinity; Bioinformatics;

   Sammanfattning : The biological functions of proteins depend on their physical interactions with other molecules, such as proteins and peptides. Therefore, modeling the protein-ligand interactions is important for understanding protein functions in different biological processes. LÄS MER

3. 12. Method development and applications of Pyrosequencing technology

   Författare :Baback Gharizadeh; KTH; []
   Nyckelord :apyrase; bacterial identification; dATP?S; EST sequencing; fungal identification; human papillomavirus HPV ; microbial and viral typing; multiple sequencing primer method; Pyrosequencing technology; Sequenase; single-stranded DNA-binding protein SS;

   Sammanfattning : The ability to determine nucleic acid sequences is one ofthe most important platforms for the detailed study ofbiological systems. Pyrosequencing technology is a relativelynovel DNA sequencing technique with multifaceted uniquecharacteristics, adjustable to different strategies, formatsand instrumentations. LÄS MER

4. 13. Everyday mining : Exploring sequences in event-based data

   Författare :Katerina Vrotsou; Matthew Cooper; Anders Ynnerman; Kajsa Ellegård; Andrew S. Harvey; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Event-based data; activity diary data; event-sequences; interactive exploration; sequence identification; visual data mining; Computer science; Datavetenskap;

   Sammanfattning : Event-based data are encountered daily in many disciplines and are used for various purposes. They are collections of ordered sequences of events where each event has a start time and a duration. LÄS MER

5. 14. Arrayed identification of DNA signatures

   Författare :Max Käller; Lundeberg Joakim; Mats Nilsson; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; apyrase; allele-specific extension; competitive hybridization; DNA sequencing; genotyping; human papillomavirus HPV ; MC1R; microarray; mutation; p53; protease; Bioengineering; Bioteknik;

   Sammanfattning : In this thesis techniques are presented that aim to determine individual DNA signatures by controlled synthesis of nucleic acid multimers. Allele-specific extension reactions with an improved specificity were applied for several genomic purposes. Since DNA polymerases extend some mismatched 3’-end primers, an improved specificity is a concern. LÄS MER

7. 15. Sequence based identification of genetic variation associated with intellectual disability

   Författare :Jin Zhao; Lars Feuk; Anna Lindstrand; Uppsala universitet; []
   Nyckelord :;

   Sammanfattning : Intellectual disability (ID) is a common neurodevelopmental condition, often caused by genetic defects. De novo variation (DNV) is an important cause of ID, especially in severe or syndromic forms of the disorder. Next generation sequencing has been a successful application for finding pathogenic variation in ID patients. LÄS MER