Sökning: "sentinel node"

Visar resultat 6 - 10 av 44 avhandlingar innehållade orden sentinel node.

  1. 6. Sentinel node based immunotherapy of cancer

    Författare :Mona Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The tumor draining lymph node, the sentinel node, is regarded as a valuable station for staging and evaluating prognoses for patients with cancer. The object of this thesis was to investigate the immune response against solid cancers and to explore the sentinel node as a source of naturally occurring tumor reactive lymphocytes, for further activation and expansion in vitro for the purpose of immunotherapy. LÄS MER

  2. 7. Superparamagnetic iron oxide nanoparticles, a novel tracer in breast cancer surgery

    Författare :Abdi-Fatah Hersi; Staffan Eriksson; Fredrik Wärnberg; Andreas Karakatsanis; Thorsten Kühn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; superparamagnetic iron oxide nanoparticles; SPIO; magnetic seed; magnetic surgery; sentinel node; sentinel node biopsy; nonpalpable; ductal carcinoma in situ; DCIS; Surgery; Kirurgi;

    Sammanfattning : The most common surgical choice of treatment in breast cancer is breast-conserving surgery (BCS) together with sentinel lymph node biopsy (SNB). Around 10% of breast cancer diagnosis are ductal carcinoma in situ (DCIS). Superparamagnetic iron oxide nanoparticles (SPIO) are a novel tracer for sentinel lymph node (SN) detection. LÄS MER

  3. 8. Multimodal sentinel lymph node imaging using nanoscale-tailored particles; The importance of particle size

    Författare :Pontus Kjellman; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; multimodal contrast agent; USPIO; sentinel lymph node; in vivo; EL-4 tumor;

    Sammanfattning : As a cancer grows it will, at a certain stage of disease progression, start spreading in the body. For several types of cancer this spreading will first occur through the lymphatic system and the first place where metastatic cell will be encountered is the first lymph node that drains the area where the tumor is located. LÄS MER

  4. 9. Detecting prostate cancer metastases - PET/CT and the sentinel node technique

    Författare :Henrik Kjölhede; Malmö Urologisk cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Metastases; PET CT; Choline; Fluoride; Sentinel lymph nodes;

    Sammanfattning : Prostate cancer is one of the most common malignancies. Its treatment is highly dependent on the presence or absence of metastases. The available invasive and non-invasive modalities for detecting metastases are imperfect. LÄS MER

  5. 10. Predictors of Lymph Node Metastasis in Primary Breast Cancer - Risk Models for Tailored Axillary Management

    Författare :Looket Dihge; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; Axillary lymph node dissection; Sentinel lymph node biopsy; Ultrasonography; Nomogram; Artificial neural network; Gene Expression; Prediction model;

    Sammanfattning : Most patients with breast cancer present with low-risk tumors, node-negative disease, and excellent prognosis. For these patients, routine axillary nodal staging by sentinel lymph node biopsy (SLNB) has no therapeutic benefit. For patients with limited sentinel lymph node metastasis, completion axillary nodal dissection is controversial. LÄS MER