Sökning: "sentinel node biopsy"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden sentinel node biopsy.

  1. 1. Sentinel Node Biopsy in Breast Cancer : Clinical and Immunological Aspects

    Författare :Jana de Boniface; Leif Bergkvist; Annika Håkansson; Omgo Nieweg; Uppsala universitet; []
    Nyckelord :Surgery; breast cancer; tumour immunology; sentinel node biopsy; CD3-zeta; CD28; Kirurgi;

    Sammanfattning : The most important prognostic factor in breast cancer is the axillary lymph node status. The sentinel node biopsy (SNB) is reported to stage the axilla with an accuracy > 95 % in early breast cancer. Tumour-related perturbation of T-cell function has been observed in patients with malignancies, including breast cancer. LÄS MER

  3. 2. Sentinel Node in Clinical Practice : Implications for Breast Cancer Treatment and Prognosis

    Författare :Yvette Andersson; Leif Bergkvist; Jan Frisell; Jana de Boniface; Robert Mansel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; sentinel node; micrometastases; survival; non-sentinel node metastases;

    Sammanfattning : The introduction of sentinel lymph node biopsy (SLNB) has conveyed several new issues, such as the risk of false negativity, long-term consequences, the prognostic significance of micrometastases and whether ALND can be omitted in sentinel lymph node- (SLN) positive patients.Archived SLN specimens from 50 false negative patients and 107 true negative controls were serially sectioned and stained with immunohistochemistry. LÄS MER

  4. 3. Sentinel Node Biopsy for Breast Cancer : Aspects and evolution

    Författare :Andreas Karakatsanis; Fredrik Wärnberg; Peter Stålberg; Helena Olofsson; Lisa Rydén; Uppsala universitet; []
    Nyckelord :Breast Cancer; Sentinel Node Biopsy; Superparamagnetic Iron Oxide;

    Sammanfattning : Sentinel Node Biopsy (SNB) in clinical practice was pivotal to the shaping of modern diagnosis, staging and treatment of patients with breast cancer. The use of radioisotope (RI) and blue dye (BD) has led to high detection rates with low false negatives, but delivery-of-care limitations connected to these tracers as well as the need for methods addressing new clinical conundrums delineates the urge for new tracers with comparable performance, easier logistics and, ideally expanded implementations. LÄS MER

  5. 4. Sentinel lymph node biopsy in endometrial cancer

    Författare :Barbara Geppert; Lund Obstetrik och gynekologi; []
    Nyckelord :Endometrial cancer; Sentinel lymph node biopsy; Lymphadenectomy; Lymphatic Metastasis; Lymphatic system; Lymphatic complications; Indocyanine green; Robotic surgery;

    Sammanfattning : .... LÄS MER

  7. 5. Superparamagnetic iron oxide nanoparticles, a novel tracer in breast cancer surgery

    Författare :Abdi-Fatah Hersi; Staffan Eriksson; Fredrik Wärnberg; Andreas Karakatsanis; Thorsten Kühn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; superparamagnetic iron oxide nanoparticles; SPIO; magnetic seed; magnetic surgery; sentinel node; sentinel node biopsy; nonpalpable; ductal carcinoma in situ; DCIS; Surgery; Kirurgi;

    Sammanfattning : The most common surgical choice of treatment in breast cancer is breast-conserving surgery (BCS) together with sentinel lymph node biopsy (SNB). Around 10% of breast cancer diagnosis are ductal carcinoma in situ (DCIS). Superparamagnetic iron oxide nanoparticles (SPIO) are a novel tracer for sentinel lymph node (SN) detection. LÄS MER