Sökning: "sensory neuropeptide antagonists"

Hittade 2 avhandlingar innehållade orden sensory neuropeptide antagonists.

  1. 1. Contribution of the sensory nervous system : an experimental study in the rat

    Författare :Olle Löfgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :edema; hindpaw withdrawal latency HWL ; inflammation; microcirculation; scalding; sensory nervous system; sensory neuropeptide antagonists; sensory neuropeptides; thermal injury;

    Sammanfattning : The pathophysiological background to burn induced inflammatory reactions is poorly understood and present therapy options are limited. A model of thermal injury was developed to enable investigations of the acute inflammatory reactions in the periphery as well as of the transmission of nociception at the spinal cord level. LÄS MER

  3. 2. Brain galanin sytems and their role in depression-like behaviour

    Författare :Eugenia Kuteeva; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :5-HT1A receptor; depression-like behaviour; forced swim test; galanin; galanin-overexpressing; galanin receptor; noradrenaline; serotonin; transgenic mouse;

    Sammanfattning : The aim of the present thesis was to investigate the role of the neuropeptide galanin and galanin receptor subtypes in behavioural functions with a particular focus on depression-like behaviour. In agreement with its wide distribution in the central nervous system, galanin has been implicated in various functions, including regulation of reproduction, endocrine functions, antinociception, attention, learning and memory as well as regulation of mood. LÄS MER