Sökning: "semicarbazide-sensitive amine oxidase"

Hittade 5 avhandlingar innehållade orden semicarbazide-sensitive amine oxidase.

  1. 1. Structural Studies of Echinococcus granulosus Fatty-acid-binding Protein 1 and Human Semicarbazide-sensitive Amine Oxidase

    Författare :Emma Jakobsson; Gerard Kleywegt; Andrea Mattevi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; semicarbazide-sensitive amine oxidase; vascular adhesion protein-1; copper-containing amine oxidase; fatty-acid-binding protein; Echinococcus granulosus; crystal structure; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The parasite Echinococcus granulosus causes hydatid disease, a major zoonosis. A fatty-acid-binding protein, EgFABP1, is important for the parasite, as it must acquire almost all its lipids from its environment or the host. The structure of EgFABP1 has been solved and refined to 1.6 Å resolution. LÄS MER

  2. 2. Semicarbazide-sensitive amine oxidase and vascular complications in diabetes mellitus : Biochemical and molecular aspects

    Författare :Jenny Nordquist; Keith F. Tipton; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; diabetes; SSAO; VAP-1; retinopathy; methylamine; aminoacetone; hydralazine; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Plasma activity of the enzyme semicarbazide-sensitive amine oxidase (SSAO; EC.1.4.3. LÄS MER

  3. 3. Amine oxidases in dental pulp : a study with special regard to a semicarbazide-sensitive amine oxidase with catalytic potency towards serotonin

    Författare :Astrid Norqvist-Sjöberg; Lars Oreland; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The amine oxidizing capacity of piglet dental pulp tissue has been investigated. At least six separate enzyme activities could be distinguished:- a soluble semicarbazide-sensitive (SSAO) activity towards benzylamine, most likely to be derived from the content of blood plasma within the pulp tissue;- a soluble pulp tissue SSAO activity with most properties in common with the plasma enzyme, however with great efficiency not only regarding benzylamine but also tryptamine;- a tissue bound SSAO activity with activity towards benzylamine, tryptamine, tyramine and ß-phenylethylamine;- a tissue bound semicarbazide-sensitive activity towards serotonin (SSA0-5HT) (a combination of properties never reported before);- a mitochondrially bound and clorgyline-sensitive monoamine oxidase-A (MAO-A) activity with activity towards serotonin;- a mitochondrially bound and deprenyl-sensitive MAO-B activity with activity towards e. LÄS MER

  4. 4. Semicarbazide-sensitive Amine Oxidase (SSAO) – Regulation and Involvement in Blood Vessel Damage with Special Regard to Diabetes : A Study on Mice Overexpressing Human SSAO

    Författare :Camilla Göktürk; Lars Oreland; Karin Forsberg-Nilsson; Dan Larhammar; Peter Yu; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; amine oxidases; VAP-1; vascular complications; diabetes; blood pressure; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : Semicarbazide-sensitive amine oxidase (SSAO, EC 1.4.3.6) belongs to a family of copper-containing amine oxidases. LÄS MER

  5. 5. Early diagnosis of diabetic retinopathy by mass examinations in primary health care

    Författare :Lars B Bäcklund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :amaurosis - amine oxidase copper-containing - benzylamine - blindness - diabetes mellitus complications - diabetic retinopathy - Estonia - HbA1c - he services - services research - hemoglobin A; glycosylated - incidence - mass screening - methylamine - photo graphy - physicians; family - prevalence - population - primary health care - prospective studies - registries - rehabilitation centers - semicarbazide-sensitive amine oxidase SSAO -Sweden - vascular adhesion protein- I - vision screening - vision; subnormal - visual acuity;

    Sammanfattning : The general objective of this thesis was to describe a system for fundus photography for early diagnosis of diabetic retinopathy, performed by mobile teams visiting primary health care centres in Stockholm County. Large-scale implementation showed this method to be feasible, acceptable, and popular. LÄS MER