Sökning: "selenoprotein"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet selenoprotein.

  1. 1. Selenoprotein P. Nutritional and clinical aspects

    Författare :Marie Persson Moschos; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Food and drink technology; oxidant defense; LDL-apheresis; European survey; selenium supplementation; cancer risk; selenium status; radioimmunoassay; selenoprotein P; human plasma; Livsmedelsteknik; Fysicumarkivet A:1999:Persson Moschos;

    Sammanfattning : In this thesis, the nutritional regulation and clinical significance of selenoprotein P (SeP) in human plasma of healthy and diseased subjects was investigated. For the analysis of SeP, a radioimmunoassay was developed using polyclonal antibodies. LÄS MER

  3. 2. Selenoproteins in the Bovine Mammary Gland. Regulation of mRNA and Protein Expression

    Författare :Katharina Bruzelius; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Livsmedelsteknik; Food and drink technology; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; milk; Natural science; cancer; prolactin; insulin; hydrocortisone; retinoic acid; MAC-T; northern blot; two-dimensional electrophoresis; bovine mammary gland; selenium; selenoprotein;

    Sammanfattning : Selenium is a micronutrient that is essential for many important life processes due to the action of the specific selenoproteins containing one or more of the 21st amino acid, selenocysteine. Twenty-five selenoprotein genes have been found in the human genome but the function of many of them is not yet known. LÄS MER

  4. 3. Tenomodulin, serum amyloid A and the serum amyloid A receptor selenoprotein S – implications for metabolic disease

    Författare :Maja Olsson; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Obesity and obesity-related metabolic diseases are associated with a low-grade inflammation, including slightly increased serum levels of the acute phase protein serum amyloid A (A-SAA). A-SAA is one amongst several adipose tissue (AT) produced proteins suggested to influence development of metabolic diseases. LÄS MER

  5. 4. Expression of thioredoxin reductase 1 in mammalian cells with regulation by the core promoter and use of alternative splice variants

    Författare :Anna-Klara Rundlöf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Redox regulation; thioredoxin reductase; TXNRD1; selenoprotein; promoter; transcription; alternative splicing; expression;

    Sammanfattning : Reactive oxygen species are generated in cells as by-products of aerobic metabolism. To protect from damaging effects the cells possess several antioxidant systems and one of the most important is the thioredoxin system. LÄS MER

  7. 5. Selenocysteine in proteins : properties and biotechnological use

    Författare :Linda Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Selenocysteine; recombinant selenoprotein production; thioredoxin reductase; enzymology; protein labeling; mite allergy; mouse model;

    Sammanfattning : Selenocysteine (Sec), the 21st amino acid, exists in all kingdoms of life and has unique biochemical properties, such as high electrophilicity and low pKa. The highly increased reactivity of selenoenzymes compared to their sulfur-containing cysteine-dependent homologs is generally regarded as the evolutionary reason for having selenoproteins. LÄS MER