Sökning: "selenium"

Visar resultat 11 - 15 av 111 avhandlingar innehållade ordet selenium.

  1. 11. Studies on Redox-proteins and Cytokines in inflammation and Cancer

    Författare :Akter Hossain; Anders Rosén; Christer Lindqvist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thioredoxin Trx ; Selenium; Tumor necrosis factor TNF ; Cancer; nflammation; oxidative stress; Protein-disulfide isomerase PDI ; Tumor necrosis factor receptor TNFR ; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The redox state in the cell plays a major role in determining vital functions and its major imbalance can lead to severe cell injury or death. Redox active proteins and cytokines involved in this process includes thioredoxin (Trx), protein disulfide isomerase (PDI), and tumor necrosis factor (TNF) superfamilies. LÄS MER

  3. 12. Clinical characteristics and prognosis of peripartum cardiomyopathy

    Författare :Kamilu Musa Karaye; Michael Henein; Krister Lindmark; Maria Schaufelberger; Umeå universitet; []
    Nyckelord :peripartum cardiomyopathy; characteristics; survival; selenium; RV dysfunction; Cardiology; kardiologi;

    Sammanfattning : Background:Peripartum cardiomyopathy (PPCM) is an incompletely understood disease that causes significant morbidity and mortality in many parts of the world, including Northern Nigeria. The aims of this Thesis were: [1] to determine if selenium deficiency, serum ceruloplasmin and traditional birth practices are risk factors for PPCM, in Kano, Nigeria; [2] to describe the one year survival and left ventricular reverse remodeling (LVRR) in a group of patients with PPCM from three referral hospitals in Kano, Nigeria; [3] to identify potential electrocardiographic (ECG) predictors of PPCM; and [4] to assess right ventricular systolic dysfunction (RVSD) and remodelling in a cohort of PPCM patients in Kano, Nigeria. LÄS MER

  4. 13. Regenerable Organochalcogen Antioxidants : An Explorative Study

    Författare :Jiajie Yan; Lars Engman; David J. Procter; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; autoxidation; antioxidant; selenium; tellurium; regenerable; multifunctional; radical-trapping; hydroperoxide-decomposing; co-antioxidant; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : Antioxidants are widely used to protect organic materials from damages caused by autoxidation, an oxidation process that occurs under normal aerobic conditions. In this thesis, novel multifunctional organoselenium and organotellurium antioxidants were designed, synthesized, and evaluated in search for compounds with better radical-trapping capacity, regenerability, and hydroperoxide-decomposing ability. LÄS MER

  5. 14. Design, Synthesis and Evaluation of Catalytic Chalcogenide Antioxidants

    Författare :David Shanks; Lars Engman; John C Walton; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; antioxidant; tellurium; selenium; computational design; homolytic substitution; radical cyclisation; microwave-assisted synthesis; antioxidant regeneration; Organisk kemi; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis describes the design, synthesis and evaluation of novel chalcogenide antioxidants.A computational model for the prediction of antioxidant properties of chalcogen-containing antioxidants has been developed. LÄS MER

  7. 15. Prostate Cancer; Metabolic Risk Factors, Drug Utilisation, Adverse Drug Reactions

    Författare :Birgitta Grundmark; Lars Holmberg; Björn Zethelius; Gunnar Engström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Epidemiology; Pharmacoepidemiology; Metabolic Syndrome; Selenium; Smoking; hOGG1; MnSOD; Competing Risk; Adherence; Persistance; Medical Possession Ratio; MPR; Signal Detection; PRR; proportional reporting ratio; ULSAM; PcBaSE; EudraVigilance; SPDR; Swedish Prescribe Drug Registry; NPCR; National Prostate Cancer Registry; SDR; Signal; disproportionality analysis; PRR-TA; EudraVigilance; Epidemiology; Epidemiologi; Kirurgi; särskilt urologi; Urology; Oncology; Onkologi; Geriatrics; Geriatrik;

    Sammanfattning : Increased possibilities during the last decades for early detection of prostate cancer have sparked research on preventable or treatable risk factors and on improvements in therapy. Treatments of the disease still entail significant side effects potentially affecting men during the rest of their lives. LÄS MER