Sökning: "selective serotonin-reuptake inhibitor SSRI"

Visar resultat 11 - 15 av 23 avhandlingar innehållade orden selective serotonin-reuptake inhibitor SSRI.

  1. 11. 5-HT receptor-mediated modulation of glutamate transmission in the hippocampus and prefrontal cortex and its relation to cognition and depression

    Författare :Tiberiu Loredan Stan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Depression is a multifaceted disease which is marked by cognitive and emotional memory impairments. It is characterised by an imbalacement of serotonergic and glutamatergic system in brain areas such as hippocampus and prefontal cortex. LÄS MER

  3. 12. Depression : genetic, epigenetic and DNA biobank studies

    Författare :Philippe A Melas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Depression is a disease that has an estimated lifetime prevalence of ~15% and a heritability of ~36%. There is support for a heterogeneous etiology of depression, which includes: a) numerous genetic loci, b) various epigenetic contributors, and c) different environmental risk factors. LÄS MER

  4. 13. Chiral and toxicological aspects of citalopram : an experimental study in rats

    Författare :Fredrik C. Kugelberg; Olav Spigset; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Citalopram (CIT) is a selective serotonin reuptake inhibitor (SSRI), which is used for the treatment of different psychiatric disorders. The indications for prescription of OT are linked to high risks for intentional intoxications. CIT is one of the most commonly found drugs in Swedish forensic autopsy cases. LÄS MER

  5. 14. Anxiety and depression in adolescent females : autonomic regulation and differentiation

    Författare :Eva Henje Blom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prevalence of anxiety and depression is on the increase in adolescent girls, as estimated by self-assessed symptom reports. There is a need for implementation of validated instruments to identify those in need of treatment. LÄS MER

  7. 15. Noradrenergic augmentation strategies in the pharmacological treatment of depression and schizophrenia : an experimental study

    Författare :Love Linnér; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The pharmacological treatment of depression and schizophrenia, two major psychiatric disorders, is largely based on modulation of central monoaminergic neurotransmission. However, currently available pharmacological treatment alternatives possess a relatively modest clinical efficacy, making them less than optimal. LÄS MER