Sökning: "selected reaction monitoring"
Visar resultat 11 - 15 av 15 avhandlingar innehållade orden selected reaction monitoring.
11. GC-MS based metabolomics – Development of a next generation GC-MS method and its application to nutrition and biomarker research
Sammanfattning : Metabolomics, the measurement of a broad range of small molecules in a sample, is maturing as a field in analytical chemistry and becoming a standard research tool in biological sciences for helping to generate a wider understanding of the complex biological mechanisms behind, for example, development of disease and effects of diet on health. Metabolomics analysis is generally divided into either targeted or untargeted metabolomics. LÄS MER
12. Mass Spectrometry-Based Protein Biomarker Discovery in Pancreatic Cancer
Sammanfattning : Background: Pancreatic cancer has the lowest survival rate among all the major cancer types. Although recent decades have seen advances in diagnostic imaging, surgical techniques, perioperative care and oncological treatment, this has not been translated into major improvements in clinical outcome. LÄS MER
13. Molecularly Imprinted Solid-Phase Extraction and Liquid Chromatography for Biological Samples
Sammanfattning : This thesis focuses on the use of molecularly imprinted polymers as selective sorbents for solid-phase extraction (MISPE). The MISPE methods developed were mainly intended for use with biological samples, such as human urine and blood plasma. LÄS MER
14. Volatile organic compounds from microorganisms : identification and health effects
Sammanfattning : Damp building materials are subjected to degradation processes due to moisture and also microbial growth, with both of these giving rise to emissions of volatile organic compounds (VOCs) that may contribute to indoor air health problems. The overall aim of this thesis was to investigate emissions of reactive and non-reactive VOCs from damp building materials and from the microorganisms growing on them, and also to investigate the possible health impact of these compounds. LÄS MER
15. Development and Evaluation of a Denuder-Filter System Designed for Sampling Diisocyanate Aerosols
Sammanfattning : There are many occupational environments in which isocyanates or PUR-products are used, produced or processed. During these operations there is always a risk of isocyanate exposure, which may lead to severe health problems. Isocyanates principally affect the respiratory system and they are the main cause of occupational asthma. LÄS MER