Sökning: "second primary malignancy"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden second primary malignancy.

  1. 1. The risk of second primary lung carcinoma in breast cancer patients

    Författare :Michaela Prochazka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; second primary malignancy; lung cancer; radiotherapy; smoking; validation study; familial risk;

    Sammanfattning : The overall aim of this thesis was to investigate the risk of second primary malignancies - with a special focus on lung cancer - in a cohort of approximately 152,000 Swedish women diagnosed with breast cancer between 1958 and 2000. With recent advances in early diagnosis and treatment, breast cancer is becoming an increasingly survivable disease. LÄS MER

  3. 2. Endoscopic methods for detecting malignancy in patients with ulcerative colitis and primary sclerosing cholangitis

    Författare :Bo Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ulcerative colitis; primary sclerosing cholangitis; cholangiocarcinoma; colorectal cancer; dysplasia; brush cytology; Endoscopic Retrograde Cholangiopancreatography ERCP .;

    Sammanfattning : Ulcerative colitis (UC) is a chronic ulcerative inflammatory bowel disease affecting the mucosa of the large intestine. UC patients have an increased risk for the development of colorectal cancer mainly associated with long duration and extensive involvement of the colitis. LÄS MER

  4. 3. Soft Tissue Sarcoma Patterns multiplicity, heterogeneity and growth characteristics

    Författare :Josefin Fernebro; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; Cytologi; oncology; Soft tissue sarcoma; tumor periphery; Medicine human and vertebrates ; Medicin människa och djur ; Cytology; multiple primary tumors; onkologi; cancer;

    Sammanfattning : Soft tissue sarcomas (STS) represent a group of rare and heterogenous tumors that optimally should be diagnosed and treated within multidisciplinary teams. This thesis has studied various aspects ? pathological, genetical, and clinical ? of STS. LÄS MER

  5. 4. Malignancies associated with gynecological cancer : epidemiological and etiological aspects

    Författare :Kjell Bergfeldt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neoplasms; second primary; ovarian cancer; breast cancer.;

    Sammanfattning : The aims of this thesis were to analyze the incidence and risk of second primary malignancies (SPM) in a Swedish cohort of gynecological cancer patients, to explore suggested risk factors associated with second primary malignancies in ovarian cancer patients, and to evaluate the risk of ovarian cancer in a cohort of breast cancer patients in relation to family history of breast or ovarian cancer. Incidence of second primary malignancies in 15,200 gynecologicaI cancer patients were investigated in a register-based study and compared to age- and calendar-specific incidence for women in the general population. LÄS MER

  7. 5. ANALYSIS OF NOVEL BIOMARKERS FOR UNFAVORABLE BREAST CANCER PROGNOSIS

    Författare :Emman Shubbar; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ductal Carcinoma In Situ DCIS ; Primary invasive breast cancer; Biomarkers;

    Sammanfattning : Breast cancer is the most common malignancy in women, and a major cause of mortality and morbidity despite the advances in diagnosis and treatment. The main challenge remains to identify novel biomarkers in order to improve existing treatment modalities. Ductal carcinoma in situ (DCIS) is considered as a direct precursor of invasive breast cancer. LÄS MER