Sökning: "second primary cancer"

Visar resultat 11 - 15 av 149 avhandlingar innehållade orden second primary cancer.

  1. 11. Pan-cancer study of transcriptional responses to oncogenic somatic mutations

    Författare :Arghavan Ashouri; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Driver mutations; Genomics; Transcriptomics; lncRNAs; NRF2; ALK;

    Sammanfattning : Cancer cells typically carry acquired somatic mutations in key cancer driver genes, which can be identified on the basis of recurrence in cancer cohorts. Such mutations may cause aberrant protein activity and altered gene expression in the nucleus, driving the cell toward a cancerous phenotype. LÄS MER

  3. 12. Cellular effects of ionizing radiation : Relevant for understanding cancer risk after medical and environmental radiation exposures

    Författare :Pamela Chiaka Akuwudike; Andrzej Wojcik; Lovisa Lundholm; Kerstin Borgmann; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation; DNA damage; radiation-induced carcinogenesis; second primary cancer; cisplatin chemoradiotherapy; dose fractionation; low dose; low dose rate; dose and dose rate effectiveness factor DDREF ; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Radiation-induced cancers are stochastic and delayed effects of exposure to ionizing radiation. The dose-response relationship for radiation-induced cancers at both low dose/low dose rates and high doses (doses encountered during radiotherapy) remains unclear. LÄS MER

  4. 13. Improved oncological treatment of anal cancer

    Författare :Otilia Leon; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anal cancer; chemotherapy; Radiotherapy; Prognosis and survival; phase I II trial; Cetuximab; metastatic;

    Sammanfattning : Background: Squamous cell cancer of the anus (SCCA) is a rare malignancy, but the incidence is increasing. It isassociated with humman papilloma virus infection. The standard treatment is radiotherapy (RT) combined withchemotherapy, usually 5-fluorouracil (5FU)/Mitomycin C (MMC). LÄS MER

  5. 14. Disease-Specific Survival in Prostate Cancer Patients : Results from the Scandinavian Prostate Cancer Group (SPCG) Trial No. 5 and Regional Cancer Register Data

    Författare :Rami Klaff; Folke Sjöberg; Eberhard Varenhorst; Gabriel Sandblom; Ove Andrén; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Androgen deprivation treatment; bone metastases; early failure; extent of disease; hormone-naïve; long-term disease-specific survival; low-risk; mortality; quality-of-life; predictors of survival; prostate cancer.;

    Sammanfattning : IntroductionProstate cancer (PCa) is the most common cancer among men in Sweden. The clinical course varies considerably, which makes it difficult to predict the prognosis in the individual case. In order to explore the early as well as the late course of the disease, large study groups and population-based cohorts are necessary. LÄS MER

  7. 15. Soft Tissue Sarcoma Patterns multiplicity, heterogeneity and growth characteristics

    Författare :Josefin Fernebro; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; Cytologi; oncology; Soft tissue sarcoma; tumor periphery; Medicine human and vertebrates ; Medicin människa och djur ; Cytology; multiple primary tumors; onkologi; cancer;

    Sammanfattning : Soft tissue sarcomas (STS) represent a group of rare and heterogenous tumors that optimally should be diagnosed and treated within multidisciplinary teams. This thesis has studied various aspects ? pathological, genetical, and clinical ? of STS. LÄS MER