Sökning: "scoring system"

Visar resultat 16 - 20 av 103 avhandlingar innehållade orden scoring system.

1. 16. Prognostic factors in squamous cell carcinoma of the head and neck, with emphasis on 11q13 rearrangements and cyclin D1 overexpression

   Författare :Jan Åkervall; Lund näs- och halssjukdomar Öron-; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; audiologi; Otorinolaryngologi; auditive system and speech; audiology; head and neck; squamous cell carcinoma; genetics; prognosis; CCND1; chromosomes; cyclin D1; chemotherapy; Otorhinolaryngology; gene expression; hörsel- och talorganen;

   Sammanfattning : At present, clinical outcome or response to therapy can not be fully predicted in individual cases of squamous cell carcinoma of the head and neck (SCCHN). The overall aim of the present studies was to investigate potential prognostic factors, more closely related to the malignant progression of a tumor than the established markers, such as the TNM-classification system. LÄS MER

3. 17. Microfluidic bead-based methods for DNA analysis

   Författare :Aman Russom; Ulf Gyllensten; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; single nucleotide polymorphism; DNA analysis; SNP; microfluidics; pyrosequencing; beads; lab on a chip; hybridization; DASH; microsystem; micro totat analysis system; allele-specific extension; DASH; microcontact printing; Genetik; Clinical genetics; Klinisk genetik;

   Sammanfattning : With the completion of the human genome sequencing project, attention is currently shifting toward understanding how genetic variation, such as single nucleotide polymorphism (SNP), leads to disease. To identify, understand, and control biological mechanisms of living organisms, the enormous amounts of accumulated sequence information must be coupled to faster, cheaper, and more powerful technologies for DNA, RNA, and protein analysis. LÄS MER

4. 18. Dermal exposure determinants : a pesticide exposure assessment approach for developing countries

   Författare :Luis E Blanco Romero; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Dermal exposure; pesticides; determinants of dermal exposure to pesticides; subsistence farmers; fluorescent tracer; visual scoring system;

   Sammanfattning : Background: We know little about the levels of exposure to pesticide in subsistence farmers mainly because of lack of easy to use and low cost pesticide exposure assessment methods. Aim: This thesis aimed to develop a semi-quantitative approach to assess dermal exposure to pesticides relevant for conditions in developing countries. LÄS MER

5. 19. Dermal exposure to pesticides in Nicaragua : a qualitative and quantitative approach

   Författare :Aurora Aragón; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Dermal exposure; developing country; pesticides; subsistence farmers; fluorescent tracer; visual scoring system; skin wipes; pesticide residues.;

   Sammanfattning : Background: Pesticide use continues to be a serious public health problem in developing countries, despite decades of safe pesticide use strategies. In Nicaragua, organophosphate insecticides, in particular chlorpyrifos and methamidophos are responsible for about half of the acute pesticide poisonings. LÄS MER

7. 20. Studies of anemia in the myelodysplastic syndromes

   Författare :Martin Jädersten; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Myelodysplasia; growth factors; Cox regression; delayed entry; left truncation; mortality; international prognostic scoring system; IPSS; who-classification based prognostic scoring system; WPSS; thalidomide analogue; IMiD; hematopoietic stem cell; adhesion; stroma; matrix; osteonectin; matricellular protein; NPM1; immunohistochemistry.;

   Sammanfattning : Background: The myelodysplastic syndromes (MDS) constitute a heterogeneous group of malignant bone marrow disorders, characterized by chronic anemia and increased risk of transformation to acute myeloid leukemia (AML). The first line therapy of anemia in MDS is erythropoietin (EPO) with or without granulocyte colony-stimulating factor (G-CSF). LÄS MER