Sökning: "scientist"
Visar resultat 1 - 5 av 134 avhandlingar innehållade ordet scientist.
1. Capillary electrophoresis mass spectrometry applied to structural proteomics and small molecule analysis
Sammanfattning : Capillary electrophoresis with mass spectrometric (CE–MS) detection offers a separation method without equal in terms of flexibility, utility, and cost efficiency. Here we demonstrate precisely this through the application of several laboratory-built CE–MS instruments for the separation of brain metabolites in non-primates, enantioselective separations of synthetic anesthetic metabolites in fractionated pony urine, application in structural proteomics workflows, and identification of exogenous alkaloid biotransformationproducts in human cerebrospinal fluid (CSF). LÄS MER
2. Pre-breakdown Phenomena in Mineral Oil Based Nanofluids
Sammanfattning : Mineral oil is a dielectric liquid commonly used in high voltage equipment such as power transformers. Interestingly, it has been experimentally observed that the dielectric strength of the mineral oil is improved when nanoparticles are added. LÄS MER
3. Pharmacometric Models for Antibody Drug Conjugates and Taxanes in HER2+ and HER2- Breast Cancer
Sammanfattning : In oncology, there is a need to optimize drug treatment for efficient eradication of tumors, minimization of adverse effects (AEs), and prolonging patient survival. Pharmacometric models can be developed to streamline information between drug development phases, describe and quantify response to treatment, and determine dose regimens that balance toxicity and efficacy. LÄS MER
4. Creep aspects of softwood from the cell-wall level to structures
Sammanfattning : This thesis addresses the intricate mechanical behaviour of natural materials, with a particular focus on wood. Despite millennia of use, understanding the mechanical behaviour of wood materials remains challenging due to their complex microstructures. LÄS MER
5. Gene x lifestyle interactions in type 2 diabetes mellitus and related traits
Sammanfattning : Background: Type 2 diabetes is thought to result from interactions between genetic and lifestyle factors, but few robust examples exist. The overarching aim of this thesis was to discover such interactions by studying cohorts of white youth and adults from northern Europe in which physical activity, genotypes, and diabetes-related traits or diabetes incidence had been ascertained. LÄS MER