Sökning: "scar formation"

Visar resultat 6 - 10 av 44 avhandlingar innehållade orden scar formation.

  1. 6. On optic nerve injury : experimental studies on axonal regeneration in the adult mammalian CNS

    Författare :Marcus Ohlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Astroglia; axon; degeneration; glial scar; immunohistochemistry; macrophage; methylprednisolone; microglia; neurosurgery; optic nerve; rat; regeneration and visual evoked potentials;

    Sammanfattning : Optic nerve injury may occur after a trauma to the head and in many cases it causes partial or total blindness. Today, these patients cannot be offered any specific treatment to restore visual function. LÄS MER

  3. 7. Fibrosis in the central nervous system : the role of perivascular cells

    Författare :Daniel Holl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Regeneration in the adult mammalian central nervous system (CNS) is very limited. One limiting factor is the formation of chronic scar tissue, which inhibits axonal regeneration and functional recovery. LÄS MER

  4. 8. Studies on myocardial regeneration

    Författare :Olaf Ingmar Bergmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Heart disease is one of the leading causes of adult and child morbidity and mortality. The underlying pathology leads typically to a loss of functional cardiomyocytes that causes heart failure. LÄS MER

  5. 9. Scarring and regeneration in the central nervous system

    Författare :Jannis Kalkitsas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In response to injury, tissues employ conserved reparative mechanisms to heal the damage and recover their function. The reparative success varies according to the organism, the tissue or organ, and the age of the specimen. The reparative response occurs through two separate but overlapping processes: wound healing and regeneration. LÄS MER

  7. 10. Neural progenitors for sensory and motor repair

    Författare :Jan Hoeber; Elena Kozlova; Linda Greensmith; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regenerative Neurobiology; Stem cells; Sensory regeneration; Spinal cord injury; Amyotrophic Lateral Sclerosis; Neurodegeneration; Oxidative Stress; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Injury and neurodegenerative conditions of the spinal cord can lead to paralysis and loss of sensation. Cell therapeutic approaches can restore sensory innervation of the spinal cord following injury and protect spinal cord cells from degeneration. LÄS MER