Sökning: "sacubitril"

Hittade 2 avhandlingar innehållade ordet sacubitril.

  1. 1. Bridging the gap between clinical trials and clinical practice : sacubitril-valsartan in heart failure as a model

    Författare :Helena Norberg; Krister Lindmark; Ellinor Bergdahl; Eva-Lotta Glader; Björn Wettermark; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systematic implementation; healthcare quality improvement; chronic disease management; heart failure; sacubitril-valsartan; real-world population; sex differences; kardiologi; Cardiology;

    Sammanfattning : When novel treatments prove more effective than standard therapies, a swift and effective implementation is needed to reach cost-effectiveness and to benefit eligible patients. Meanwhile, women and elderly are often under-represented in clinical trials, which creates a knowledge gap on how to optimize treatment in clinical practice. LÄS MER

  2. 2. Pathophysiology and treatment of Takotsubo Syndrome - insights from preclinical studies

    Författare :Anwar Ali Gasim Elsied; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []

    Sammanfattning : ABSTRACT Background: Takotsubo syndrome (TTS), also recognized as “stress-induced cardiomyopathy (SIC)” and “broken heart syndrome”, is an acute cardiac failure syndrome characterized by transient regional ventricular akinesia or hypokinesia, and often presents similarly to acute myocardial infarction (AMI). In contrast to AMI, the characteristic regional myocardial akinesia in TTS does not involve a culprit coronary artery. LÄS MER