Sökning: "sVEGFR-1"
Hittade 2 avhandlingar innehållade ordet sVEGFR-1.
1. Effects of sex steroids and tamoxifen on VEGF in the breast
Sammanfattning : Sex steroid exposure constitutes a risk factor for breast cancer, but little is known about the effects of sex steroids on factors mediating angiogenesis, the development of new blood vessels, in normal and malignant breast tissue. In this thesis we have investigated the effects of estradiol, progesterone, and the nonsteroidal anti-estrogen tamoxifen on vascular endothelial growth factor (VEGF) and its receptors (VEGFR-1 and VEGFR-2) in normal human breast tissue, endothelial cells, and breast cancer. LÄS MER
2. Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis
Sammanfattning : The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate to several cardiovascular risk factors, e.g. hypertension and hyperlipidemia. LÄS MER