Sökning: "rong-zhen liao"

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  1. 1. Mechanistic insights into dinuclear zinc enzymes from density functional theory studies

    Författare :Rong-Zhen Liao; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemistry; Kemi;

    Sammanfattning : In this thesis, quantum chemical methods have been used to shed light on the reaction mechanisms of several dinuclear zinc enzymes. The enzymes studied are involved in the hydrolysis of phosphates, amides, and carboxylic esters, namely RNase Z, Dihydroorotase (DHO), and N-acyl homoserine lactone hydrolase (AHL lactonase). LÄS MER