Sökning: "roland månsson"

Hittade 1 avhandling innehållade orden roland månsson.

  1. 1. Calcium-induced mitochondrial permeability transition in CNS-derived mitochondria - Pharmacological aspects of specificity and toxicity in neuroprotection

    Författare :Roland Månsson; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; mitochondria; brain; calcium; respiration; cell death; permeability transition; calcium retention; minocycline; neuroprotection; Debio 025;

    Sammanfattning : Mitochondria are the main site for energy conversion in the cell. Under certain circumstances, such as excess calcium retention or production of reactive oxygen species, a pore forms at contact sites between the outer and the normally impermeable inner mitochondrial membrane. LÄS MER