Sökning: "rodent"

Visar resultat 16 - 20 av 244 avhandlingar innehållade ordet rodent.

  1. 16. New sensitive and specific methods for sex steroid measurements in rodent serum and tissues

    Författare :Maria E. Nilsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex steroids; mass spectrometry; rodents;

    Sammanfattning : Accurate measurement of sex steroids (androgens, estrogens, and progesterone) is essential in research and clinical settings for common diseases including osteoporosis, prostate cancer, breast cancer, and cardiovascular diseases. Sex steroids are not only produced in the gonads and adrenals but may also be locally synthesized in peripheral target tissues. LÄS MER

  3. 17. Methods to study glymphatic system in the rodent brain during physiological and pathological processes

    Författare :Roberta Battistella; Glia-Immune Interactions; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glymphatic system; Aquaporin-4; Lectins; Parkinson´s disease; α-synuclein; Hypothermia;

    Sammanfattning : Over the past decade, our understanding of brain-waste clearance underwent a revolution after the discovery of the so-called glymphatic system. The glia-lymphatic (abbreviated, glymphatic) system was first described in 2012 as a paravascular macrosystem involved in the distribution of nutrients and clearance of metabolic waste from the brain parenchyma. LÄS MER

  4. 18. Variation at candidate gene loci and their fuctional importance in rodent models of ethanol dependence

    Författare :Karl Björk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : As genetic research has progressed, psychiatric disorders, including the addictions have emerged as moderately heritable. For alcoholism, the overall heritability has been estimated from twin studies to range between 50 to 60%. LÄS MER

  5. 19. Exploring dual-lipopolysaccharide exposure on schizophrenia-like behavior and the kynurenine pathway in rodent models

    Författare :Yiran Zheng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immune activation contributes to the pathophysiology of schizophrenia. The kynurenine pathway, serving as the primary route of tryptophan catabolism, has been posited as a potential link between immune activation and the manifestation of symptoms associated with schizophrenia. LÄS MER

  7. 20. The attenuation of the P53 response to DNA damage in rodent liver preneoplastic enzyme-altered foci

    Författare :Niklas Finnberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Enzyme-altered foci; p53; ATM; diethylnitrosamine; phenobarbital; liver; gene dosage;

    Sammanfattning : In connection with life-time bioassays in rodents, the liver is one of the organs most frequently affected. During the carcinogenic process, single preneoplastic hepatocytes develop into hepatocellular adenoma or carcinoma (HCC). LÄS MER