Sökning: "rocks"
Visar resultat 1 - 5 av 276 avhandlingar innehållade ordet rocks.
1. Dissolving the Rocks : Solubility Enhancement of Active Pharmaceutical Ingredients using Mesoporous Silica
Sammanfattning : Poor aqueous solubility is one of the greatest barriers for new drug candidates to enter toxicology studies, let alone clinical trials. This thesis focuses on contributing to solving this problem, evaluating the oral toxicity of mesoporous silica particles, and enhancing the apparent solubility and bioavailability of active pharmaceutical ingredients in vitro and in vivo using mesoporous silica particles. LÄS MER
2. Ice, wood and rocks : regulating elements in riverine ecosystems
Sammanfattning : Riparian ecosystems are of great importance in the landscape, connecting landscape elements longitudinally and laterally and often encompassing sharp environmental gradients in ecological processes and communities. They are influenced by fluvial disturbances such as flooding, erosion and sediment deposition, which create dynamic and spatially heterogeneous habitats that support a high diversity of species. LÄS MER
3. Strength and deformability of fractured rocks
Sammanfattning : This thesis presents a systematic numerical modeling framework to simulate the stress-deformation and coupled stress-deformation-flow processes by performing uniaxial and biaxial compressive tests on fractured rock models with considering the effects of different loading conditions, different loading directions (anisotropy), and coupled hydro-mechanical processes for evaluating strength and deformability behavior of fractured rocks. By using code UDEC of discrete element method (DEM), a series of numerical experiments were conducted on discrete fracture network models (DFN) at an established representative elementary volume (REV), based on realistic geometrical and mechanical data of fracture systems from field mapping at Sellafield, UK. LÄS MER
4. Stress Effects on Solute Transport in Fractured rocks
Sammanfattning : The effect of in-situ or redistributed stress on solute transport in fractured rocks is one of the major concerns for many subsurface engineering problems. However, it remains poorly understood due to the difficulties in experiments and numerical modeling. LÄS MER
5. Solute transport through fractured rocks : the influence of geological heterogeneities and stagnant water zones
Sammanfattning : To describe reactive solute transport and retardation through fractured rocks, three models are developed in the study with different focuses on the physical processes involved and different simplifications of the basic building block of the heterogeneous rock domain. The first model evaluates the effects of the heterogeneity of the rock matrix and the stagnant water zones in part of the fracture plane. LÄS MER