Sökning: "rheumatoid"

Visar resultat 21 - 25 av 494 avhandlingar innehållade ordet rheumatoid.

  1. 21. Rheumatoid Arthritis in a 10-Year Perspective, Outcome for Patients Followed from Early Disease

    Författare :Elisabet Lindqvist; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; rheumatology locomotion; Skelett; COMP; Skeleton; muscle system; Anti-IL-1alpha; Anti-CCP; Rheumatoid factor isotypes; Mortality; Radiographic progression; Joint damage; Disease activity; HAQ; SOFI; Disability; Prognosis; Rheumatoid arthritis; Outcome;

    Sammanfattning : Rheumatoid arthritis (RA) is characterized by persistent inflammation, progressive joint damage and disability. This thesis describes the outcome after 10 years in a cohort of 183 RA patients (116 women, 67 men) recruited 1985-89. The mean age was 51 years and symptom duration 11 months at inclusion. LÄS MER

  3. 22. Aspects of Disability in Rheumatoid Arthritis : a five-year follow-up in the Swedish TIRA project

    Författare :Mathilda Björk; Björn Gerdle; Ingrid Thyberg; Thomas Skogh; Klas Rikner; Karin Harms-Ringdahl; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis RA ; disability; hand function; pain intensity; ADL; sick leave; prediction; Rheumatology; Reumatologi;

    Sammanfattning : Rheumatoid arthritis (RA) is a progressive disease, often leading to disability. Because the disease course develops rapidly during the first years after diagnosis, more knowledge is needed about the early disease course to minimize later disability. LÄS MER

  4. 23. Genetic Studies of Rheumatoid Arthritis using Animal Models

    Författare :Niklas Nordquist; William Dietrich; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Complex disease; autoimmune; rheumatoid arthritis; genetic; mapping; QTL; locus; linkage; animal model; rat; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. LÄS MER

  5. 24. The role of B cells in rheumatoid arthritis

    Författare :Maria Rehnberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; Rheumatoid arthritis; B cell depletion therapy;

    Sammanfattning : It has been known for a long time that B cells play a role in rheumatoid arthritis (RA). By production of autoantibodies, presentation of auto-antigens and by producing cytokines B cells may contribute to the pathogenesis of RA. In recent years it has been shown that anti-B cell therapy is a powerful tool in the treatment of RA. LÄS MER

  7. 25. Rheumatoid Arthritis: Body Composition, Bone Loss, and Mortality

    Författare :Christina Book; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fat mass; bone mass; lean mass; body composition; mortality; rheumatoid arthritis; predictors;

    Sammanfattning : Early rheumatoid arthritis (RA) patients (disease duration ≤1 year, n=165) were recruited 1995-2001 and followed systematically clinically and with dual energy X-ray absorptiometry (DXA) over 2 years and compared to age- and gender-matched controls. Baseline arm and leg lean mass were decreased in RA patients in both genders and body mass index and truncal fat distribution were increased in female RA patients. LÄS MER