Sökning: "rhesus prophylaxis"

Hittade 4 avhandlingar innehållade orden rhesus prophylaxis.

1. 1. A Search for the Masked Mechanism Behind IgG-Mediated Suppression of Antibody Responses

   Författare :Joakim Bergström; Birgitta Heyman; Jenny Hallgren Martinsson; Frida Henningsson Johnson; Mats Bemark; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FcγR; complement; sheep erythrocytes; IgG-mediated immune suppression; rhesus prophylaxis; rhesus D antigen; germinal center; Immunologi; Immunology;

   Sammanfattning : Antibodies passively administered together with their specific antigen can enhance or suppress the specific antibody response. This phenomenon is known as antibody feedback regulation. Whether this modulation causes up- or downregulation of the antibody response depends both on the antibody isotype and the antigen used. LÄS MER

3. 2. Fc receptors and feedback regulation by antibodies

   Författare :Mikael Karlsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Mouse; B lymphocytes; Fc; receptors; IgG; IgE; FcgRI; FcgRII; FcgRIII; Fc e RI; CD23; Rh prophylaxis; Haemolytic disease of the newborn; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : The purpose of this investigation was to determine the role of Fc receptors for IgG (FcγRI, FcγRIIB, FcγRIII and FcRn) in immunoregulation. IgG is known to enhance the response to soluble antigens such as bovine serum albumin whereas the response to particulate antigens is suppressed. LÄS MER

4. 3. Fcγ Receptors in the Immune Response

   Författare :Teresita Díaz de Ståhl; Jan van de Winkel; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Fc Receptors; IgG Receptors; IgE Receptors; Immune regulation; In vivo animal models; Mouse; Rh prophylaxis; Rheumatoid arthritis; Transgenic knockout; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : Circulating immune complexes play an important role in the modulation of antibody responses and in the pathogenesis of immune diseases. This thesis deals with the in vivo regulatory properties of antibodies and their specific Fc receptors. LÄS MER

5. 4. New strategies to prevent fetal and neonatal complications in Rhesus D immunization

   Författare :Eleonor Tiblad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The general purpose of this thesis was to investigate if fetal and neonatal complications due to RhD immunization in the mother could be prevented by 1) reducing procedure-related complications in intrauterine blood transfusions and by 2) reducing the incidence of RhD immunization by providing routine antenatal anti-D prophylaxis during pregnancy selectively to non-immunized RhD negative women with RhD positive fetuses. Paper I was a retrospective study including 284 intrauterine transfusions in 84 women 1990-2010. LÄS MER