Sökning: "rhesus D antigen"

Hittade 3 avhandlingar innehållade orden rhesus D antigen.

  1. 1. A Search for the Masked Mechanism Behind IgG-Mediated Suppression of Antibody Responses

    Författare :Joakim Bergström; Birgitta Heyman; Jenny Hallgren Martinsson; Frida Henningsson Johnson; Mats Bemark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FcγR; complement; sheep erythrocytes; IgG-mediated immune suppression; rhesus prophylaxis; rhesus D antigen; germinal center; Immunologi; Immunology;

    Sammanfattning : Antibodies passively administered together with their specific antigen can enhance or suppress the specific antibody response. This phenomenon is known as antibody feedback regulation. Whether this modulation causes up- or downregulation of the antibody response depends both on the antibody isotype and the antigen used. LÄS MER

  3. 2. Definition of immunoglobulin germline genes by next generation sequencing for studies of antigen-specific B cell responses

    Författare :Néstor Vázquez Bernat; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immunoglobulins play a critical role in the adaptive immune system, existing as cell surface-expressed B cell receptors and secreted antibodies. Circulating antibodies are the main correlate of protective immunity for most vaccines. LÄS MER

  4. 3. Dissection of HIV-1 Env-specific B cell responses in nonhuman primates

    Författare :Christopher Sundling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Vaccine-induced protection is generally mediated by long-lived antigen-specific B cell responses. Most licensed vaccines target pathogens that display relatively low variability, but for highly variable pathogens, such as HIV-1, vaccine development is more challenging. LÄS MER