Sökning: "reward"

Visar resultat 21 - 25 av 226 avhandlingar innehållade ordet reward.

  1. 21. Modeling Biochemical Network Involved in Striatal Dopamine Signaling

    Författare :Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez Arenas; Upinder Singh Bhalla; Jakob Kisbye Dreyer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine signaling; Striatum; Reward learning; Acetylcholine; Mass-action modeling; FRET biosensor; Adenosine; Eligibility trace; Computer Science; Datalogi;

    Sammanfattning : In this thesis, I studied the molecular integration of reward-learning related neuromodulatory inputs by striatal medium-sized projection neurons (MSNs) using mass-action kinetic modeling.It is known that, in reward learning, an unexpected reward results in transient elevation in dopamine (peak) whereas omission of an expected reward leads to transient dopamine decrease (dip). LÄS MER

  3. 22. Motion and Emotion : Functional In Vivo Analyses of the Mouse Basal Ganglia

    Författare :Emma Arvidsson; Åsa Wallén-Mackenzie; Cecilia Flores; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine; Basal Ganglia; Reward System; In Vivo Chronoamperometry; Optogenetics; Deep Brain Stimulation; Parkinson’s Disease; Addiction; Glutamate; Vesicular Glutamate Transporter; VGLUT2; Sex; Age; Subthalamic Nucleus; Striatum; Nucleus Accumbens; Ventral Tegmental Area;

    Sammanfattning : A major challenge in the field of neuroscience is to link behavior with specific neuronal circuitries and cellular events. One way of facing this challenge is to identify unique cellular markers and thus have the ability to, through various mouse genetics tools, mimic, manipulate and control various aspects of neuronal activity to decipher their correlation to behavior. LÄS MER

  4. 23. A neuroimaging perspective on regulation of emotion, reward, and attention

    Författare :Frida Bayard; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Emotional symptoms and non-emotional symptoms such as inattention often co-occur. Each of these symptom domains covers symptoms that are distributed along a continuum across the population; from non-clinical levels to clinically significant psychiatric symptoms. LÄS MER

  5. 24. Personligt mod : Om krigsdekorationer som mjuk normstyrning under insatsen i Afghanistan åren 2008-2012

    Författare :Magna Robertsson; Jan Hallenberg; Ulrika Mörth; Anders Ivarsson Westerberg; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; metagovernance; soft norm governance; new institutionalism; logic by values; military ethics; norms; veteran policy; reward system; war decorations; Merit Medal; courage; Swedish Armed Forces; international military operations; Afghanistan; metagovernance; mjuk normstyrning; nyinstitutionalism; värdebaserad logik; professionsetik; militär yrkesetik; normer; veteranpolitik; belöningssystem; krigsdekorationer; förtjänstmedalj; mod; Försvarsmakten; internationella insatser; Afghanistan; Political Science; statsvetenskap; Ledarskap under påfrestande förhållanden;

    Sammanfattning : During the 2000s, Sweden has pursued an active foreign and security policy. This has meant participation in several international military operations and has left many Swedish soldiers and officers with combat experience. LÄS MER

  7. 25. Functional Analysis of the Vesicular Glutamate Transporter 2 in Specific Neuronal Circuits of the Brain

    Författare :Karin Nordenankar; Åsa Wallén-Mackenzie; Rainer Spanagel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Addiction; amphetamine; affective behaviour; cocaine; cognitive behaviour; conditional knockout mouse; dopamine; operant self-administration; reward system; schizophrenia; Neuroscience; Neurovetenskap;

    Sammanfattning : A key issue in neuroscience is to determine the connection between neuronal circuits and behaviour. In the adult brain, all neuronal circuits include a glutamatergic component. LÄS MER