Sökning: "restenosis"

Visar resultat 6 - 10 av 41 avhandlingar innehållade ordet restenosis.

  1. 6. Challenging the mystique Connection. Deciphering cell-matrix interactions role in atherosclerosis and restenosis

    Författare :Vignesh Murugesan; Kärlväggsbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dystrophin glycoprotein complex; beta-sarcoglycan; dystrophin; Plaque; vascular smooth muscle cells; atherosclerosis; restenosis;

    Sammanfattning : Atherosclerosis is the underlying cause for myocardal infarction, stroke and peripheral arterial disease, collectively referred to as cardiovascular diseases. These represent the major cause of death globally. LÄS MER

  3. 7. Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology

    Författare :Yuri Sheikine; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atherosclerosis; coronary artery disease; restenosis; chemokines; eicosanoids;

    Sammanfattning : Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel wall. These processes are mediated, among other substances, by molecules belonging to a large family of chemoattractants. LÄS MER

  4. 8. Retinoids in the modulation of vascular inflammation

    Författare :Andreas Gidlöf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Retinoids; metabolism; vascular smooth muscle cell; nitric oxide; inflammation; proliferation; restenosis;

    Sammanfattning : Vascular disease is multifactorial. Smooth muscle cells, the major constituent of the normal vessel wall, play a pivotal role. The pathogenesis includes cellular differentiation, proliferation and inflammatory activation. LÄS MER

  5. 9. Perlecan in vascular disease

    Författare :Tran Phan Kiet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Perlecan; heparan sulfate; smooth muscle cells; intimal hyperplasia; vascular disease; atherosclerosis; restenosis; heparin-binding growth factor.;

    Sammanfattning : Atherosclerosis has become the most common cause of death in the world. The development of the disease involves accumulation of lipids in the inner layer of the vessel wall, the intima, and recruitment of inflammatory cells and smooth muscle cells (SMCs). LÄS MER

  7. 10. Prevention of intimal hyperplasia after balloon angioplasty and / or stent insertion. or How to mend a broken heart - Just say NO

    Författare :Jan Harnek; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; Remodeling. Endothelium-derived factors. Self-expanding stents. Restenosis. Scanning -electron microscopy. Endothelial factors. Nitric oxide. Intimal hyperplasia. Angioplasty. Stents. Interventional procedures. Endothelium.;

    Sammanfattning : Background: Restenosis is the most frequently occurring adverse event after percutaneous intravascular treatment of atherosclerotic lesions, which limits long-term patency of the intervention. Objective: The aim of the study was to evaluate if minimizing vascular injury during treatment by insertion of self-expanding stents or modifying the reparative mechanisms by local drug delivery can reduce restenosis. LÄS MER