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Visar resultat 1 - 5 av 157 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Wiring Components of the Respiratory Chain : Modulation of the Respiratory Chain in Yeast and Bacteria

   Författare :Jacob Schäfer; Peter Brzezinski; Dennis Winge; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cytochrome c oxidase; Electron transfer; Membrane protein; Ligand; Kinetics; Mechanism; Rcf1; Cytochrome c; Respiratory supercomplex; Cryo-electron microscopy; Biochemistry; biokemi;

   Sammanfattning : The enzyme complexes of the respiratory chain are organized in supramolecular assemblies, so-called respiratory supercomplexes. In the yeast Saccharomyces cerevisiae, these supercomplexes consist of two copies of complex III (bc1 complex) and one or two copies of complex IV (cytochrome c oxidase, CytcO). LÄS MER

3. 2. Mechanistic Insights in the Biogenesis and Function of the Respiratory Chain

   Författare :Hannah Dawitz; Martin Ott; Cristina Ugalde; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; respiratory chain; bc1 complex; cytochrome c oxidase; Cbp3; Rcf1; Rcf2; respiratory supercomplexes; biogenesis; mitochondria; Saccharomyces cerevisiae; Biochemistry; biokemi;

   Sammanfattning : Mitochondria fulfill a plethora of functions, including harboring metabolic pathways and converting energy stored in metabolites into ATP, the common energy source of the cell. This last function is performed by the oxidative phosphorylation system, consisting of the respiratory chain and the ATP synthase. LÄS MER

4. 3. Phthalates: A Full Chain Story : Connecting phthalate sources, indoor dust, human intake, and airway symptoms in children

   Författare :Anna-Sofia Preece; Carl-Gustav Bornehag; Malin Knutz; Huan Shu; Bruce Lanphear; Karlstads universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; children s health; endocrine disruption; exposure pathways; full chain model; human exposure; plasticizers; pregnancy; PVC; respiratory; SELMA study; Public Health Science; Folkhälsovetenskap;

   Sammanfattning : Phthalates are widely used in a large number of consumer goods and building materials from which they can leach and contaminate the environment such as indoor dust and air. It is unclear how phthalate sources in our homes and indoor dust contribute to human intake and airway symptoms in children. LÄS MER

5. 4. Structural characterisation of mitochondrial macromolecular complexes using cryo-EM : Mitoribosome biogenesis and respiratory chain supercomplex

   Författare :Sorbhi Rathore; Martin Ott; Daniel Wilson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitoribosome biogenesis; mitoribosome assembly factors; yeast respiratory supercomplexes; single particle electron cryo-microscopy; cryo-EM sample preparation; Biochemistry; biokemi;

   Sammanfattning : Mitochondria, popularly known as powerhouse of the cell, contain specialised mitoribosomes that synthesise essential membrane proteins. These essential proteins are required to form enzyme complexes, which carry out the process of oxidative phosphorylation (OXPHOS). LÄS MER

7. 5. Prokaryotic respiratory supercomplexes : Studies of interactions between complexes III and IV

   Författare :Olga Stah; Pia Ädelroth; Petra Hellwig; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bioenergetics; membrane protein; bacterial respiration; electron transport chain; supercomplex; cytochrome c oxidase; membrane-anchored cytochrome c; cytochrome bc1 complex; electron transfer; proton transfer; time-resolved spectroscopy; apoptosis; biokemi; Biochemistry;

   Sammanfattning : Respiratory processes for cellular energy conversion are carried out by the membrane-associated enzymes of the electron transfer chain (ETC). In recent years there has been emerging data showing that the members of the ETC organize into higher-level assemblies called supercomplexes (SCs) whose functional relevance is not yet fully understood. LÄS MER