Sökning: "researcher"

Visar resultat 1 - 5 av 521 avhandlingar innehållade ordet researcher.

  1. 1. Dynamic soil-structure interaction of simply supported high-speed railway bridges

    Författare :Johan Lind Östlund; Jean-Marc Battini; Andreas Andersson; Mahir Ülker-Kaustell; Rui Calçada; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Dynamic soil-structure interaction; Railway bridge; Impedance function; Soil dynamics; High-speed train; Structural Engineering and Bridges; Bro- och stålbyggnad;

    Sammanfattning : Research performed on the subject of dynamic soil-structure interaction (SS) concerning railway bridges is presented in this thesis with the focus on simply supported railway bridges supported by shallow foundations in soil strata on bedrock. The research aims to obtain insight into the SSI of high-speed railway bridges and to provide recommendations on how to model the soil-bridge system from a design perspective. LÄS MER

  3. 2. Evaluation of biomedical microwave sensors : Microwave sensors as muscle quality discriminators in laboratory and pilot clinical trial settings

    Författare :Viktor Mattsson; Robin Augustine; Mauricio Perez; Roger Karlsson; Ayca Özcelikkale; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microwave sensors; Sarcopenia; Muscle quality assessment; Biomedical applications; Tissue dielectric properties; Data-driven modelling; Clinical trials; EM Simulations; Phantom experiments; Teknisk fysik med inriktning mot elektronik; Engineering Science with specialization in Electronics;

    Sammanfattning : In this thesis the primary focus is on the evaluation of biomedical microwave sensor to be used in the muscle analyzer system. Lower muscle quality is one indicator that a patient can have sarcopenia. Therefore the muscle analyzer system can be a tool used in screening for sarcopenia. LÄS MER

  4. 3. Nuclear safeguards directed to the application of multivariate analysis techniques to existing and future nuclear fuel cycles

    Författare :Vaibhav Mishra; Sophie Grape; Zsolt Elter; Erik Branger; Peter Dendooven; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nuclear safeguards; nuclear fuel verification; spent fuel; molten salt reactors; machine learning.; Fysik med inriktning mot tillämpad kärnfysik; Physics with specialization in Applied Nuclear Physics;

    Sammanfattning : For as long as nuclear power has existed, there has been a concern for effectively safeguarding nuclear material since it was learned that it could be misused. Early on, many nations were interested in nuclear power, and therefore there was an urgent need to verify that it was only used for civilian purposes. LÄS MER

  5. 4. LL-37-derived cyclic antimicrobial drug leads : Design, synthesis, activity and different ways of creating them 

    Författare :Taj Muhammad; Ulf Göransson; Sunithi Gunasekera; Adam A. Strömstedt; Wang Guangshun; Uppsala universitet; []
    Nyckelord :antimicrobial peptide; host defense; antimicrobial; LL-37; KR-12; peptide cyclisation; peptide dimerisation; croos-linking; cyanobactin-macrocyclase; PatGmac; butelase 1; enzymatic cyclisation; immobilisation; Farmakognosi; Pharmacognosy;

    Sammanfattning : In an era where last-line antibiotics are failing, one of the powerful approaches to develop novel therapeutic agents is to turn back to nature in order to identify possible drug candidates. Among the potential candidates, antimicrobial peptides (AMPs) have garnered much attention as an antimicrobial. LÄS MER

  7. 5. The Epigenome of Multiple Myeloma : From genome-wide analysis to pharmacological manipulation

    Författare :Alba Atienza Párraga; Helena Jernberg-Wiklund; Fredrik Öberg; Antonia Kalushkova; Miguel Angel Peinado; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Multiple myeloma; epigenetics; Polycomb; EZH2; miRNA; DNA methylation; inhibitor.; Experimentell patologi; Experimental Pathology;

    Sammanfattning : Nowadays epigenetic dysregulation is known to play a crucial role in virtually all cancers. In multiple myeloma (MM), an extensively heterogeneous malignancy, the key common feature among patients is the gene silencing imposed by the PRC2 complex through the addition of H3K27me3. LÄS MER