Sökning: "reproductive tract"
Visar resultat 1 - 5 av 54 avhandlingar innehållade orden reproductive tract.
1. Reproductive toxicology of endocrine disruptors : effects of cadmium, phthalates and phytoestrogens on testicular steroidogenesis
Sammanfattning : A number of investigations during the last two decades describe adverse trends in male reproductive health, which have been proposed to be caused by environmental factors with endocrine disrupting properties. In contrast to many other toxicants, endocrine disruptors often do not show linear dose-response relationships typical of those found in traditional toxicological studies. LÄS MER
2. Biological Markers of Fertility
Sammanfattning : Infertility affects 15 % of couples, which corresponds to 60 - 80 million worldwide. The microenvironments in which the oocyte, embryo and fetus mature are vital to the establishment and development of a healthy pregnancy. LÄS MER
3. G protein-coupled estrogen receptor 1 (GPER) in the female reproductive tract: from physiology to cancer
Sammanfattning : Estrogen effects are mediated either through genomic action involving the classical estrogen receptors, estrogen receptor alpha (ERα) and beta (ERß), which function as transcription factors in the nucleus, or through rapid non-genomic action via receptors associated with plasma membrane. Recently, a member of the G protein-coupled receptor family was ascribed estrogen receptor properties and proposed as a candidate for mediating non-genomic estrogen signaling. LÄS MER
4. Host epithelium integrity in the female reproductive tract during Neisseria gonorrhoeae infection
Sammanfattning : Neisseria gonorrhoeae infections are asymptomatic in approximately fifty percent of the affected women. Left untreated, this can develop into a long-term inflammatory state with detrimental secondary complications such as ectopic pregnancy and sterility. Furthermore, studies have shown that N. LÄS MER
5. Aspects of biliary tract cancer : incidence and reproductive risk factors
Sammanfattning : Biliary tract cancer, including cancer of the extra-hepatic bile ducts, cancer of the Ampulla of Vater and gallbladder cancer, is a devastating disease with poor prognosis. The incidence of biliary tract cancer is decreasing worldwide, for unknown reasons. LÄS MER